Differences in Adverse Drug Events Among Pediatric Patients With and Without Cancer: Sub-Analysis of a Retrospective Cohort Study

Differences in Adverse Drug Events Among Pediatric Patients With and Without Cancer: Sub-Analysis... Drugs - Real World Outcomes (2017) 4:167–173 DOI 10.1007/s40801-017-0115-8 ORIGINAL RESEARCH ARTICLE Differences in Adverse Drug Events Among Pediatric Patients With and Without Cancer: Sub-Analysis of a Retrospective Cohort Study 1 2 1 1 • • • • Akira Koizumi Yoshinori Ohta Mio Sakuma Rika Okamoto 1 3,4 1 • • Chisa Matsumoto David W. Bates Takeshi Morimoto Published online: 4 August 2017 The Author(s) 2017. This article is an open access publication Abstract patients and 289 ADEs among 213 non-cancer patients (7.1 Objectives This study investigated the differences in the per patient vs. 0.25 per patient, respectively; p\ 0.0001). incidence and severity of adverse drug events (ADEs) in The most common medications associated with ADEs in pediatric patients with and without cancer. cancer patients were antitumor agents; in contrast, medi- Methods We used data from the Japan Adverse Drug cations associated with fatal or life-threatening ADEs in Events Study for pediatrics, a cohort study enrolling cancer patients were most often sedatives (25%) and blood pediatric inpatients at two tertiary care teaching hospitals in products (25%). Medications associated with fatal or life- Japan. ADEs were identified by on-site review of all threatening ADEs among non-cancer patients were most medical http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Drugs - Real World Outcomes Springer Journals

Differences in Adverse Drug Events Among Pediatric Patients With and Without Cancer: Sub-Analysis of a Retrospective Cohort Study

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Publisher
Springer International Publishing
Copyright
Copyright © 2017 by The Author(s)
Subject
Medicine & Public Health; Pharmacotherapy; Pharmacology/Toxicology; Internal Medicine
ISSN
2199-1154
eISSN
2198-9788
D.O.I.
10.1007/s40801-017-0115-8
Publisher site
See Article on Publisher Site

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