Diethylamine-catalyzed environmentally benign synthesis of 1-oxo-hexahydroxanthenes and bis-coumarins at ambient temperature

Diethylamine-catalyzed environmentally benign synthesis of 1-oxo-hexahydroxanthenes and... 2 (4-Hydroxycoumarin) OH OH Diethylamine X = H OO O CHO 1 2 R R OH O O R = H, Cl, Br, OMe, NO , etc. 2 (Cyclic-1,3-diketone) R R Diethylamine O 1 X = OH Keywords Domino reactions  1-Oxo-hexahydroxanthenes  Bis-coumarins Tetraketones  Diethylamine & Uday V. Desai; Organic Chemistry Division, Department of Chemistry, Shivaji University, Kolhapur 416004, India Polymer Science and Engineering Division, CSIR, National Chemical Laboratory, Pune 411008, India 123 6314 R. V. Kupwade et al. Introduction The main current issues in the synthesis of complex organic molecules are improvement of efficiency, avoidance of toxic agents, reduction in waste and responsible utilization of natural sources. In this context, use of domino reactions involving the participation of two or more substrates is of relevance both from economic and ecological points of view [1–4]. Amongst domino reactions, Knoevenagel–Michael domino reactions have emerged as a powerful strategy in the synthesis of various oxa- as well as aza-heterocycles [5, 6]. In recent years, construction of xanthene scaffolds has attracted much attention of organic chemists due to their importance in the field of medicine as well as material science [7–11]. Two important classes of compounds containing a Research on Chemical Intermediates Springer Journals

Diethylamine-catalyzed environmentally benign synthesis of 1-oxo-hexahydroxanthenes and bis-coumarins at ambient temperature

Loading next page...
Springer Netherlands
Copyright © 2016 by Springer Science+Business Media Dordrecht
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial