2 (4-Hydroxycoumarin) OH OH Diethylamine X = H OO O CHO 1 2 R R OH O O R = H, Cl, Br, OMe, NO , etc. 2 (Cyclic-1,3-diketone) R R Diethylamine O 1 X = OH Keywords Domino reactions 1-Oxo-hexahydroxanthenes Bis-coumarins Tetraketones Diethylamine & Uday V. Desai email@example.com; firstname.lastname@example.org Organic Chemistry Division, Department of Chemistry, Shivaji University, Kolhapur 416004, India Polymer Science and Engineering Division, CSIR, National Chemical Laboratory, Pune 411008, India 123 6314 R. V. Kupwade et al. Introduction The main current issues in the synthesis of complex organic molecules are improvement of efﬁciency, avoidance of toxic agents, reduction in waste and responsible utilization of natural sources. In this context, use of domino reactions involving the participation of two or more substrates is of relevance both from economic and ecological points of view [1–4]. Amongst domino reactions, Knoevenagel–Michael domino reactions have emerged as a powerful strategy in the synthesis of various oxa- as well as aza-heterocycles [5, 6]. In recent years, construction of xanthene scaffolds has attracted much attention of organic chemists due to their importance in the ﬁeld of medicine as well as material science [7–11]. Two important classes of compounds containing a
Research on Chemical Intermediates – Springer Journals
Published: Feb 8, 2016
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