Die Gefäßwiderstandserhöhung bei der postischämischen Reperfusion mit niedrigem Perfusionsdruck

Die Gefäßwiderstandserhöhung bei der postischämischen Reperfusion mit niedrigem Perfusionsdruck Abb. 1  Zeitlicher The experiments were carried out in Goet- Verlauf des arteriel- tinger miniature pigs in three experimental len Perfusions- groups: group A: healthy animals (n=8), druckes (PAP perf.) group C: animals as a model for hypercapil- während der Reper- larization (n=8),and group R: animals as a fusion in den ver- schiedenen Versuchs- model for hypocapillarization (capillary rare- gruppen (A, C, R, K). faction) (n=9). Darstellung der Mit- The goal was to observe microcirculato- telwerte ry and locally hemodynamic alterations dur- ing 6 h of ischemia and subsequent reperfu- sion lasting 12 h. For this purpose systemi- cally hemodynamic,locally hemodynamic, Außerdem bildeten wir zum Vergleich Die Narkose wurde bei jeder Opera- and microcirculatory parameters were mea- eine Kontrollgruppe K (n=3) mit intra- tion durch EKG- und Pulsoxymeter-Mo- sured dynamically. operativer Belastung aber ohne akute nitoring, rektalr Thermometrie sowie The acute ischemia was induced by Ischämie bzw. ohne Reperfusion. arterielle und venöse Blutgasanalyse clamping the right common iliac artery and In Vorversuchen zur Entwicklung überwacht. Ebenso wurden verschiede- the collateral vessels,setting up a mass liga- einer Hyperkapillarisierung wurde in ne Laborparameter (Elektrolyte, Blut- ture,and positioning the right hind leg verti- Gruppe C eine chronische Ischämie für bild usw.) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Gefässchirurgie Springer Journals

Die Gefäßwiderstandserhöhung bei der postischämischen Reperfusion mit niedrigem Perfusionsdruck

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Copyright © 2002 by Springer-Verlag Berlin Heidelberg
Medicine & Public Health; Vascular Surgery
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