Curr Diab Rep (2017) 17:82 DOI 10.1007/s11892-017-0909-9 MICROVASCULAR COMPLICATIONS—RETINOPATHY (JK SUN AND PS SILVA, SECTION EDITORS) Toke Bek Springer Science+Business Media, LLC 2017 Abstract Introduction Purpose of Review The diameter of retinal vessels is an im- portant source of information about retinal blood flow and Background metabolism. The purpose of the present study is to review how diameter changes of retinal vessels contribute to the de- The retina has a dual blood supply with the choroidal vascular velopment of diabetic retinopathy and may be a marker of the system supplying the outer retinal layers and the retinal vas- prognosis of the disease. cular system that is visible by ophthalmoscopy supplying the Recent Findings The early stages of diabetic retinopathy are inner layers, with the watershed zone being located approxi- accompanied with dilatation of the diameter of retinal vessels mately at the outer plexiform layer . The inner retinal vas- and reduced autoregulation. Diabetic retinopathy also shows cular system varies among different species and is extensively regional differences in the macular area and the retinal periph- developed in humans, monkeys, pigs, and small rodents. ery and accompanying differences in vascular reactivity in Unfortunately, the inner vascular system is sparse in
Current Diabetes Reports – Springer Journals
Published: Aug 8, 2017
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