Journal of Anesthesia (2018) 32:313–315 https://doi.org/10.1007/s00540-018-2509-5 EDITORIAL Shinju Obara Received: 2 February 2018 / Accepted: 12 May 2018 / Published online: 15 May 2018 © Japanese Society of Anesthesiologists 2018 Keywords Dexmedetomidine · General anesthesia · Intraoperative · Pain management Introduction the usefulness of dexmedetomidine as an adjuvant to con- ventional general anesthesia using propofol or inhaled anes- Newly introduced anesthetic agents are sometimes clini- thetics and opioids has been investigated [3, 4]. With the cally used in cases of unapproved indication when the drug’s anesthetic-sparing property of dexmedetomidine, a reduc- mechanisms of action are considered to be reasonable. tion in individual doses of anesthetics is also expected to Dexmedetomidine, a highly selective α-2-adrenoceptor reduce side effects. agonist, has sedative and analgesic effects without respira- In the recent issues of the Journal of Anesthesia, a variety tory depression. In Japan, dexmedetomidine was approved of applications of dexmedetomidine that may possibly be in 2004 as a sedative in patients during and after mechani- clinical workable alternatives have been reported. cal ventilation in the intensive care setting. The frequency of dexmedetomidine use was low immediately after its introduction into clinical practice, which may partly Pretreatment with dexmedetomidine be because its use was limited to up to
Journal of Anesthesia – Springer Journals
Published: May 15, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud