Development of GATE Monte Carlo simulation for a CsI pixelated gamma camera dedicated to high resolution animal SPECT

Development of GATE Monte Carlo simulation for a CsI pixelated gamma camera dedicated to high... GATE is currently considered in scintigraphic imaging as a powerful tool to develop, design and optimize nuclear medicine modalities. This paper describes the GATE simulation of a pixelated gamma camera which is dedicated to high resolution of small animals imaging. It consists of a CsI(Na) crystal array coupled to position sensitive photomultiplier tube. The simulation model includes photon tracking through low energy high resolution hexagonal parallel holes collimator, CsI(Na) pixelated crystal, back-compartment, and camera shielding. Simulations were compared with experimental results by some criteria such as energy spectrum, energy resolution, spatial resolution, sensitivity and count profiles obtained from line and point sources imaging. The acquired energy resolution show good agreement with measured spectra. Difference between calculated and experimental values is about 0.3% for absolute sensitivity measurement. The result of the image uniformity is more consistent after implementation of non-uniformity correction. These values were about 1.3 and 1.2% for experimental and simulation study in the central field of view, respectively. Measurements showed that the spatial resolutions differences at the head surface along the long dimensions of gamma camera for simulation and experimental differed by no more than 4%.Differences along the short axis were about 6%. The FWHMs of images of point and line sources show good consistency between experimental images and corresponding simulated ones. The difference between experimental and simulated system parameters was within 11%. Our results demonstrate the ability and flexibility of the Monte Carlo simulation for modeling pixelated gamma camera with position sensitive detector by selecting the appropriate parameters for digitizer chain and collimator position on the detector surface. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Australasian Physical & Engineering Sciences in Medicine Springer Journals

Development of GATE Monte Carlo simulation for a CsI pixelated gamma camera dedicated to high resolution animal SPECT

Loading next page...
 
/lp/springer_journal/development-of-gate-monte-carlo-simulation-for-a-csi-pixelated-gamma-t98otWareN
Publisher
Springer Netherlands
Copyright
Copyright © 2017 by Australasian College of Physical Scientists and Engineers in Medicine
Subject
Biomedicine; Biomedicine, general; Biological and Medical Physics, Biophysics; Medical and Radiation Physics; Biomedical Engineering
ISSN
0158-9938
eISSN
1879-5447
D.O.I.
10.1007/s13246-017-0607-6
Publisher site
See Article on Publisher Site

Abstract

GATE is currently considered in scintigraphic imaging as a powerful tool to develop, design and optimize nuclear medicine modalities. This paper describes the GATE simulation of a pixelated gamma camera which is dedicated to high resolution of small animals imaging. It consists of a CsI(Na) crystal array coupled to position sensitive photomultiplier tube. The simulation model includes photon tracking through low energy high resolution hexagonal parallel holes collimator, CsI(Na) pixelated crystal, back-compartment, and camera shielding. Simulations were compared with experimental results by some criteria such as energy spectrum, energy resolution, spatial resolution, sensitivity and count profiles obtained from line and point sources imaging. The acquired energy resolution show good agreement with measured spectra. Difference between calculated and experimental values is about 0.3% for absolute sensitivity measurement. The result of the image uniformity is more consistent after implementation of non-uniformity correction. These values were about 1.3 and 1.2% for experimental and simulation study in the central field of view, respectively. Measurements showed that the spatial resolutions differences at the head surface along the long dimensions of gamma camera for simulation and experimental differed by no more than 4%.Differences along the short axis were about 6%. The FWHMs of images of point and line sources show good consistency between experimental images and corresponding simulated ones. The difference between experimental and simulated system parameters was within 11%. Our results demonstrate the ability and flexibility of the Monte Carlo simulation for modeling pixelated gamma camera with position sensitive detector by selecting the appropriate parameters for digitizer chain and collimator position on the detector surface.

Journal

Australasian Physical & Engineering Sciences in MedicineSpringer Journals

Published: Dec 11, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off