Elimination of the heat-sensitive l(2)M167 DTS mutation from artificial Drosophila melanogaster populations at constant temperature 25°C and various frequencies of the mutation in the parental generation was studied. Components of fitness of the l(2)M167 DTS mutation were estimated in the artificial populations by means of the recurrent model of the dependence of the frequency of this mutation in a given generation on its frequency in the previous generation. The model was solved by a numerical method with limitations on the values of some fitness components obtained in test experiments. According to the limitations and frequencies of the l(2)M167 DTS mutation, the leading role and limits of the variation in egg-to-adult viability and female fertility were determined. The previously suggested effect of the positive selection for viability of individuals heterozygous for l(2)M167 DTS was confirmed.
Russian Journal of Genetics – Springer Journals
Published: Jul 15, 2005
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