Detection of melanoma metastases with the sentinel node biopsy: the legacy of Donald L. Morton, MD (1934–2014)

Detection of melanoma metastases with the sentinel node biopsy: the legacy of Donald L. Morton,... Dr. Donald L. Morton was clearly the pioneer of the sentinel node biopsy, which was a major advance in oncology that has improved the management of cancer patients worldwide. He conducted a series of practice-changing clinical trials to validate the important staging role of the sentinel lymph node biopsy for melanoma, and also spawned other studies that demonstrated its staging value in multiple other cancer types, most notably in breast cancer, gastric cancer, and colorectal cancer. His many contributions in this field have provided a unique opportunity to study host/tumor relationships, since the sentinel lymph node is the first location were the host immune defenses are confronted with metastasis arising from the primary cancer. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical & Experimental Metastasis Springer Journals

Detection of melanoma metastases with the sentinel node biopsy: the legacy of Donald L. Morton, MD (1934–2014)

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media B.V., part of Springer Nature
Subject
Biomedicine; Cancer Research; Biomedicine, general; Oncology; Hematology; Surgical Oncology
ISSN
0262-0898
eISSN
1573-7276
D.O.I.
10.1007/s10585-018-9908-8
Publisher site
See Article on Publisher Site

Abstract

Dr. Donald L. Morton was clearly the pioneer of the sentinel node biopsy, which was a major advance in oncology that has improved the management of cancer patients worldwide. He conducted a series of practice-changing clinical trials to validate the important staging role of the sentinel lymph node biopsy for melanoma, and also spawned other studies that demonstrated its staging value in multiple other cancer types, most notably in breast cancer, gastric cancer, and colorectal cancer. His many contributions in this field have provided a unique opportunity to study host/tumor relationships, since the sentinel lymph node is the first location were the host immune defenses are confronted with metastasis arising from the primary cancer.

Journal

Clinical & Experimental MetastasisSpringer Journals

Published: May 31, 2018

References

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