Design and electrochemical measurement of a current-mode analog-to-time converter with short-pulse output capability using local intra-cell activation for high-speed time-domain biosensor array

Design and electrochemical measurement of a current-mode analog-to-time converter with... This study demonstrates a current-mode analog-to-time converter (CMATC) enabling short-pulse output capability by using the newly-proposed local intra-cell activation technique, which contributes to the development of high-speed time-domain biosensor array. In the conventional CMATC, the activation pulse is generated globally at the periphery. This limits the output pulse width because of the considerable parasitic word-line capacitance. In this study, a shorter pulse output was achieved by generating the activation pulse locally by using intra-cell configuration without being affected by word-line capacitances. In 1024 × 1024 configuration, 77% pulse width reduction was confirmed using SPICE simulation. A test chip was fabricated using a 0.6 µm standard CMOS process. The measurement results obtained using a sensor chip demonstrate the expected input–output characteristic and 3.36 ns pulse output. Finally, we measure the change in potential with respect to the ratio of the ion concentration, by using Fe(CN) 6 3− and Fe(CN) 6 4− as the oxidant and reductant, respectively. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Analog Integrated Circuits and Signal Processing Springer Journals

Design and electrochemical measurement of a current-mode analog-to-time converter with short-pulse output capability using local intra-cell activation for high-speed time-domain biosensor array

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Engineering; Circuits and Systems; Electrical Engineering; Signal,Image and Speech Processing
ISSN
0925-1030
eISSN
1573-1979
D.O.I.
10.1007/s10470-017-1003-6
Publisher site
See Article on Publisher Site

Abstract

This study demonstrates a current-mode analog-to-time converter (CMATC) enabling short-pulse output capability by using the newly-proposed local intra-cell activation technique, which contributes to the development of high-speed time-domain biosensor array. In the conventional CMATC, the activation pulse is generated globally at the periphery. This limits the output pulse width because of the considerable parasitic word-line capacitance. In this study, a shorter pulse output was achieved by generating the activation pulse locally by using intra-cell configuration without being affected by word-line capacitances. In 1024 × 1024 configuration, 77% pulse width reduction was confirmed using SPICE simulation. A test chip was fabricated using a 0.6 µm standard CMOS process. The measurement results obtained using a sensor chip demonstrate the expected input–output characteristic and 3.36 ns pulse output. Finally, we measure the change in potential with respect to the ratio of the ion concentration, by using Fe(CN) 6 3− and Fe(CN) 6 4− as the oxidant and reductant, respectively.

Journal

Analog Integrated Circuits and Signal ProcessingSpringer Journals

Published: Jun 24, 2017

References

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