Depression severity and concentration difficulties are independently associated with HRQOL in patients with unipolar depressive disorders

Depression severity and concentration difficulties are independently associated with HRQOL in... Qual Life Res (2017) 26:2459–2469 DOI 10.1007/s11136-017-1595-4 Depression severity and concentration difficulties are independently associated with HRQOL in patients with unipolar depressive disorders 1 2 3 4 5 • • • • • A. Fattori L. Neri A. Bellomo M. Vaggi C. Mencacci the ILDE Study Group Accepted: 9 May 2017 / Published online: 13 May 2017 Springer International Publishing Switzerland 2017 Abstract SF-12 domains. Additionally, we observed a strong asso- Purpose Cognitive impairment is a core feature of major ciation between concentration difficulties and all HRQOL depressive disorder (MDD), and dysfunctions in this area outcomes independent of other symptoms of depression strongly contribute to MDD-associated disability. Whether and robust to adjustment for possible confounders. cognitive impairment has an independent clinical course Conclusions Our data corroborate previous findings sug- and a unique impact on HRQOL is still debated. We sought gesting that cognitive impairment is a feature of unipolar to characterize the relationship between depression severity depressive disorders partially independent of the severity and HRQOL, evaluating the burden of concentration dif- of other symptoms, and may represent a specific target of ficulties on HRQOL. therapy with a strong impact on patients’ functioning and Methods Six hundred ninety-two patients with http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Quality of Life Research Springer Journals

Depression severity and concentration difficulties are independently associated with HRQOL in patients with unipolar depressive disorders

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Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing Switzerland
Subject
Medicine & Public Health; Quality of Life Research; Sociology, general; Public Health; Quality of Life Research
ISSN
0962-9343
eISSN
1573-2649
D.O.I.
10.1007/s11136-017-1595-4
Publisher site
See Article on Publisher Site

Abstract

Qual Life Res (2017) 26:2459–2469 DOI 10.1007/s11136-017-1595-4 Depression severity and concentration difficulties are independently associated with HRQOL in patients with unipolar depressive disorders 1 2 3 4 5 • • • • • A. Fattori L. Neri A. Bellomo M. Vaggi C. Mencacci the ILDE Study Group Accepted: 9 May 2017 / Published online: 13 May 2017 Springer International Publishing Switzerland 2017 Abstract SF-12 domains. Additionally, we observed a strong asso- Purpose Cognitive impairment is a core feature of major ciation between concentration difficulties and all HRQOL depressive disorder (MDD), and dysfunctions in this area outcomes independent of other symptoms of depression strongly contribute to MDD-associated disability. Whether and robust to adjustment for possible confounders. cognitive impairment has an independent clinical course Conclusions Our data corroborate previous findings sug- and a unique impact on HRQOL is still debated. We sought gesting that cognitive impairment is a feature of unipolar to characterize the relationship between depression severity depressive disorders partially independent of the severity and HRQOL, evaluating the burden of concentration dif- of other symptoms, and may represent a specific target of ficulties on HRQOL. therapy with a strong impact on patients’ functioning and Methods Six hundred ninety-two patients with

Journal

Quality of Life ResearchSpringer Journals

Published: May 13, 2017

References

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