PharmacoEconomics (2017) 35:777–791 DOI 10.1007/s40273-017-0514-4 SYSTEMATIC REVIEW Deﬁning and Measuring the Affordability of New Medicines: A Systematic Review 1 2,3 4 5 • • • • Fernando Anton˜anzas Robert Terkola Paul M. Overton Natalie Shalet 3,6,7 Maarten Postma Published online: 5 May 2017 Springer International Publishing Switzerland 2017 Abstract thresholds and restrictions, to identify articles describing a Background In many healthcare systems, affordability deﬁnition of affordability with respect to new medicines. concerns can lead to restrictions on the use of expensive Additional deﬁnitions were identiﬁed through citation efﬁcacious therapies. However, there does not appear to be searching, and through manual searches of European health any consensus as to the terminology used to describe technology assessment body websites. affordability, or the thresholds used to determine whether Results In total, 27 deﬁnitions were included in the review. new drugs are affordable. Of these, ﬁve deﬁnitions described affordability in terms of Objectives The aim of this systematic review was to the value of a product; seven considered affordability investigate how affordability is deﬁned and measured in within the context of healthcare system budgets; and 15 healthcare. addressed whether products are affordable in a given Methods MEDLINE, EMBASE and EconLit databases country based
PharmacoEconomics – Springer Journals
Published: May 5, 2017
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