Data Wisdom in Computational Genomics Research

Data Wisdom in Computational Genomics Research All fields of science are now inundated with massive amounts of data, which have the potential to answer fundamental questions. Genomics is one particular example, exploring questions like: How does the human genome work? What genome variants make us more prone to diseases? To find answers to these questions, it is crucial to develop statistical and machine learning methods that can scale up, particularly through efficient data storage and communication. Equally crucial, but less emphasized, is the possession of data wisdom—a rebranding of the best elements of applied statistics in a recent note at ODBMS.org ( http://www.odbms.org/2015/04/data-wisdom-for-data-science/ ). The note at ODBMS.org contains ten sets of questions a practitioner can ask to cultivate data wisdom. Although there has been much recent excitement about big data, having enough data relevant to the problem is the key to gaining meaningful answers in genomics. Data wisdom gives us the insight into how these data would look, how much information a dataset really contains, and how to extract it. In this paper, we expand on the ten sets of questions and illustrate where and how data wisdom can be integrated into computational genomics research. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Statistics in Biosciences Springer Journals

Data Wisdom in Computational Genomics Research

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Publisher
Springer US
Copyright
Copyright © 2017 by International Chinese Statistical Association
Subject
Statistics; Statistics for Life Sciences, Medicine, Health Sciences; Biostatistics; Theoretical Ecology/Statistics
ISSN
1867-1764
eISSN
1867-1772
D.O.I.
10.1007/s12561-016-9173-9
Publisher site
See Article on Publisher Site

Abstract

All fields of science are now inundated with massive amounts of data, which have the potential to answer fundamental questions. Genomics is one particular example, exploring questions like: How does the human genome work? What genome variants make us more prone to diseases? To find answers to these questions, it is crucial to develop statistical and machine learning methods that can scale up, particularly through efficient data storage and communication. Equally crucial, but less emphasized, is the possession of data wisdom—a rebranding of the best elements of applied statistics in a recent note at ODBMS.org ( http://www.odbms.org/2015/04/data-wisdom-for-data-science/ ). The note at ODBMS.org contains ten sets of questions a practitioner can ask to cultivate data wisdom. Although there has been much recent excitement about big data, having enough data relevant to the problem is the key to gaining meaningful answers in genomics. Data wisdom gives us the insight into how these data would look, how much information a dataset really contains, and how to extract it. In this paper, we expand on the ten sets of questions and illustrate where and how data wisdom can be integrated into computational genomics research.

Journal

Statistics in BiosciencesSpringer Journals

Published: Aug 21, 2017

References

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