Current Strategy of Fetal Therapy II: Invasive Fetal Interventions

Current Strategy of Fetal Therapy II: Invasive Fetal Interventions Invasive fetal intervention provides potential benefits to the fetus, but risks to the mother and the fetus are not negligible. Large congenital pulmonary airway malformation (CPAM) may cause fetal hydrops. Shunt placement in macrocystic type or steroids administration in microcystic type CPAM have been reported to reverse the hydrops in a small case series. In selected cases of fetal congenital diaphragmatic hernia (CDH), tracheal plugging may prevent egress of the lung fluid, promote lung proliferation, and maturation of pulmonary vasculature, which favor survival in isolated right-sided CDH fetuses or those with a lung-to-head ratio of ≤1.0. Fetoscopic cystoscopy with laser fulguration of the posterior urethral valve improves the 6-month survival and renal function. A randomized controlled trial to validate the real benefits of this procedure is still underway. Laser photocoagulation of anastomosing vessels is the standard of care for severe mid-trimester twin-to-twin transfusion syndrome. The principle of equipoise is likely to be reached on the issue of optimal treatment for Quintero stage I disease. Open fetal surgery has been offered in some cases of fetal tumor and myelomeningocele (MMC). Alternatively, endoscopic approach is being investigated to minimize procedure-related maternal morbidity. Only when procedure-related complications are properly prevented and managed, it is expected that invasive therapeutic innovation will then improve perinatal outcomes of selected fetal conditions. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Fetal Medicine Springer Journals

Loading next page...
 
/lp/springer_journal/current-strategy-of-fetal-therapy-ii-invasive-fetal-interventions-cTYoLUkoHt
Publisher
Springer India
Copyright
Copyright © 2017 by Society of Fetal Medicine
Subject
Medicine & Public Health; Maternal and Child Health; Diagnostic Radiology; Ultrasound; Obstetrics/Perinatology; Reproductive Medicine
ISSN
2348-1153
eISSN
2348-8859
D.O.I.
10.1007/s40556-017-0132-4
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial