PharmacoEconomics & Outcomes News 784, p11 - 12 Aug 2017 Cryotherapy or cervical cancer screening in HIV-infected women? Preventative cryotherapy without screening is less costly for preventing cervical cancer in HIV-infected women and leads to higher life expectancy than screening strategies, according to the results of a study conducted in Kenya. The study used a Markov model to assess health outcomes and costs of the following strategies for preventing cervical cancer: 1) screening strategies including Papanicolaou (Pap) smear, visual inspection with acetic acid (VIA), human papillomavirus (HPV) testing, Pap + HPV and VIA + Pap; or 2) preventative cryotherapy without screening. The model was populated with clinical and resource-use data from a study of cervical cancer screening conducted at an HIV treatment clinic in Nairobi, Kenya. The model showed that cryotherapy without screening had the lowest mean lifetime cost of screening and treatment, compared with VIA, Pap screening and HPV screening ($US99 vs $196, $219 and $223, respectively, from a societal perspective; and $19 vs $94, $124 and $113, respectively, from a clinic perspective) and the highest life expectancy (17.3 vs 17.1 years). Among the screening strategies, VIA had the lowest cost with the highest life expectancy. However, if HPV screening could be reduced to a single-visit strategy, it would be less costly than VIA. Cryotherapy "merits further investigation as a treatment tool that could help all women enrolled in an HIV clinic," suggest the researchers. Zimmermann MR, et al. Cost-effectiveness of cervical cancer screening and preventative cryotherapy at an HIV treatment clinic in Kenya. Cost Effectiveness and Resource Allocation : 14 Jul 2017. Available from: URL: https:// doi.org/10.1186/s12962-017-0075-6 803261913 1173-5503/17/0784-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 12 Aug 2017 No. 784
PharmacoEconomics & Outcomes News – Springer Journals
Published: Aug 12, 2017
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