Objective Retinol-binding protein 4 (RBP4) and leptin are GCF and serum markers of inflammatory activity in CP and both adipokines and involved in the pathophysiology of dif- obesity, which further longitudinal studies are needed. ferent vascular and inflammatory diseases and selectively el- . . . evated in patients with obesity. The aim of the present study Keywords Chronic periodontitis Inflammation Obesity was to determine and correlate the levels of RBP4 and leptin Gingival crevicular fluid in gingival crevicular fluid (GCF) and serum in patients with chronic periodontitis (CP) and obesity. Materials and methods A total of 70 patients with age group Introduction 25 to 45 years were divided into four groups based on gingival index (GI), probing depth (PD), clinical attachment level Obesity is defined as the abnormal accumulation and storage (CAL), body mass index (BMI) and radiographic evidence of fat in adipose tissue. It may have unfavourable effect on of bone loss. The groups were (1) group I (non-obese peri- health leading to disability and death . According to the odontally healthy), (2) group II (obese periodontally healthy), WHO World Health Statistics Report 2014, overweight were (3) group III (non-obese with chronic periodontitis) and (4) more than 1.9
Clinical Oral Investigations – Springer Journals
Published: Dec 8, 2016
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