Patient https://doi.org/10.1007/s40271-018-0317-5 OR IGINAL RESEARCH ARTIC L E Converting Parkinson-Speciﬁc Scores into Health State Utilities to Assess Cost-Utility Analysis 1 2,3 4,5 • • • Gang Chen Miguel A. Garcia-Gordillo Daniel Collado-Mateo 6 4 7 • • • Borja del Pozo-Cruz Jose´ C. Adsuar Jose´ Manuel Cordero-Ferrera 3 3 Jose´ Marı´a Abella´n-Perpin˜a´n Fernando Ignacio Sa´nchez-Martı´nez Springer International Publishing AG, part of Springer Nature 2018 Abstract MM-estimator, and the generalized linear model (GLM). Objectives The aim of this study was to compare the For both EQ-5D-3L and EQ-5D-5L, indirect response Parkinson’s Disease Questionnaire-8 (PDQ-8) with three mapping based on an ordered logit model was also con- multi-attribute utility (MAU) instruments (EQ-5D-3L, EQ- ducted. Three goodness-of-ﬁt tests were employed to 5D-5L, and 15D) and to develop mapping algorithms that compare the models: the mean absolute error (MAE), the could be used to transform PDQ-8 scores into MAU scores. root-mean-square error (RMSE), and the intra-class corre- Methods A cross-sectional study was conducted. A ﬁnal lation coefﬁcient (ICC) between the predicted and sample of 228 evaluable patients was included in the observed utilities. analyses. Sociodemographic and clinical data were also Results Health state utility scores ranged from 0.61 (EQ- collected. Two EQ-5D questionnaires
The Patient - Patient-Centered Outcomes Research – Springer Journals
Published: Jun 7, 2018
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