Conversion of hormone and HER-2 receptor in metachronous neck metastases from breast carcinoma

Conversion of hormone and HER-2 receptor in metachronous neck metastases from breast carcinoma J Cancer Res Clin Oncol (2017) 143:1811–1814 DOI 10.1007/s00432-017-2426-2 ORIGINAL ARTICLE – CLINICAL ONCOLOGY Conversion of hormone and HER‑2 receptor in metachronous neck metastases from breast carcinoma 1 2 3 4 Andreas Nauroth · Matthias Kalder · Marion Rössler · Gunnar Wichmann · 4 4 Andreas Dietz · Susanne Wiegand Received: 4 April 2017 / Accepted: 13 April 2017 / Published online: 20 April 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract of these markers in the primary tumor. As such changes Purpose Metastases are a common event in breast cancer. can occur during disease progression, the evaluation of The expression of estrogen receptor (ER), progesterone biomarkers in metastatic sites should be mandatory, when- receptor (PR) and human epidermal growth factor recep- ever possible, to ensure that patients are receiving the most tor 2 (HER-2) is essential for therapy and prognosis, and effective treatment at all times. their conversion during disease progression potentially affects the treatment regimen. The aim was to analyze the Keywords Breast cancer · Lymph node metastases · estrogen, progesterone and HER-2 receptor expression in Estrogen · Progesterone · HER-2 · Neck metastases primary tumors and metachronous neck metastases from patients with breast cancer. Methods A retrospective Journal of Cancer Research and Clinical Oncology Springer Journals

Conversion of hormone and HER-2 receptor in metachronous neck metastases from breast carcinoma

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Springer Berlin Heidelberg
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Medicine & Public Health; Oncology; Cancer Research; Internal Medicine; Hematology
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