Controlled Release of Farmazin from Thermosensitive Gels Based on Poly(N-vinylcaprolactam)

Controlled Release of Farmazin from Thermosensitive Gels Based on Poly(N-vinylcaprolactam) With the aim to prolong the effect of a wide-spectrum antimicrobial agent, Farmazin (tylosine tartrate), this drug was immobilized on a gel of N-vinylcaprolactam-sodium itaconate copolymer, which undergoes a phase transition on heating. The phase transition, accompanied by a change in volume, in aqueous solutions of the pure copolymer gel and that with the immobilized drug was studied. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Applied Chemistry Springer Journals

Controlled Release of Farmazin from Thermosensitive Gels Based on Poly(N-vinylcaprolactam)

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Publisher
Springer Journals
Copyright
Copyright © 2004 by MAIK “Nauka/Interperiodica”
Subject
Chemistry; Chemistry/Food Science, general
ISSN
1070-4272
eISSN
1608-3296
D.O.I.
10.1023/B:RJAC.0000030380.07016.fa
Publisher site
See Article on Publisher Site

Abstract

With the aim to prolong the effect of a wide-spectrum antimicrobial agent, Farmazin (tylosine tartrate), this drug was immobilized on a gel of N-vinylcaprolactam-sodium itaconate copolymer, which undergoes a phase transition on heating. The phase transition, accompanied by a change in volume, in aqueous solutions of the pure copolymer gel and that with the immobilized drug was studied.

Journal

Russian Journal of Applied ChemistrySpringer Journals

Published: Sep 30, 2004

References

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