Monatsh Chem (2017) 148:1569–1579 DOI 10.1007/s00706-017-2012-y REVIEW Construction of electrochemical DNA biosensors for investigation of potential risk chemical and physical agents 1 1 Veronika Svitkova´ Ja´n Labuda Received: 28 March 2017 / Accepted: 28 May 2017 / Published online: 10 July 2017 Springer-Verlag Wien 2017 Abstract Biosensors are used speciﬁcally to the determi- Keywords Biosensors Electrochemistry Voltammetry nation of given analytes as well as investigation of DNA interactions DNA damage Toxic agents chemical interactions of surface attached biomolecules such as DNA including their structural damage. The suc- cessful function and utilization of the biosensor depends on Introduction selection of building parts (biomolecule, transducer, nanostructured interface, labels, and others), its construc- Nowadays, the importance of monitoring and regulating of tion tailored for a given purpose as well as arrangement of many different human health inﬂuencing parameters in the measurement experiment (batch and ﬂow-through areas such as food industry, drug development, clinical system, non-invasive sensors, etc.). This review is focused diagnoses and treatment, cosmetics, hygiene, environ- on novel and perspective building components, construc- mental protection, and others is rapidly increasing. tion ways and detection techniques used at the Detection of the presence and effects of chemicals electrochemical
Monatshefte für Chemie - Chemical Monthly – Springer Journals
Published: Jul 10, 2017
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