2018 Springer Science+Business Media, LLC
Chemistry of Natural Compounds, Vol. 54, No. 3, May, 2018
CONSTITUENT COMPOSITION AND BIOLOGICAL
ACTIVITY OF ESSENTIAL OIL FROM
E. M. Suleimen,
Zh. B. Iskakova,
R. V. Dudkin,
and P. G. Gorovoi
The monotypic genus Turczaninowia DC. (Asteraceae = Compositae) was separated by Augustin De Candolle (DC.)
from the genus Aster in 1836. The eastern Asian species Turczaninowia fastigiata (Fisch.) DC. (= Aster fastigiatus Fisch.)
grows in eastern Siberia (Dauria), southern Russian Far East (Primorsky Krai, south of Khabarovsk Krai, southeast of Amur
Region), Mongolia, northeastern China, Korea, and Japan. It is a biennial plant that inhabits grassy valley meadows and gentle
mountain slopes and flowers from July to September .
Flavonoids were observed previously in the aerial part of T. fastigiata . To the best of our knowledge, the composition
of essential oil from this plant has not been studied.
Raw material for the study was collected during flowering on Aug. 10, 2016, in the vicinity of Turii Rog, Khankaiskii
District, Primorsky Krai (Russia), in a grassy dry meadow. Specimens of the plants are preserved in the herbarium of the
Chemotaxonomy Laboratory, PIBOCh, FEB, RAS (Vladivostok) under herbarium code T. fastigiata 103606.
Essential oil was obtained from the aerial part of air-dried raw material by steam distillation in a Clevenger apparatus
for 2 h using hexane as a trap . GC-MS analysis of essential oils was carried out under conditions analogous to those in the
Table 1 shows that the main components of T. fastigiata essential oil were
-pinene (7.3%), trans-nerolidol (4.0%),
-calacorene (3.1%), spathulenol and perhydrofarnesyl acetone (2.2% each), and hexanal and
-humulene epoxide II
The cytotoxic activity of T. fastigiata essential oil was determined using the brine shrimp (Artemia salina) lethality
test . The experiments established that T. fastigiata essential oil at all tested concentrations (10, 5, and 1 mg/mL) exhibited
acute (96%) lethal toxicity, i.e., all larvae died.
The antiradical activity of the essential oils was determined as before [6, 7]. Essential oil from T. fastigiata had low
antiradical activity as compared with butylhydroxyanisole preparation.
1) Institute of Applied Chemistry, L. N. Gumilev Eurasian National University, 2 Satpaev St., Astana, 010008,
Republic of Kazakhstan, e-mail: firstname.lastname@example.org; 2) Chemotaxonomy Laboratory, G. B. Elyakov Pacific Institute
of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, 159 Prosp. 100 Let Vladivostoku, Vladivostok,
690022, Russian Federation; 3) Laboratory for Introduction and Selection of Floral and Decorative Plants, Botanical
Garden-Institute, Far Eastern Branch, Russian Academy of Sciences, 142 Makovskii St., Vladivostok, 690024,
Russian Federation; 4) Far-Eastern Federal University, 8 Sukhanova St., Vladivostok, 690091, Russian Federation. Translated
from Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2018, pp. 507–508. Original article submitted December 22, 2017.