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Mammalian Genome 10, 1036–1038 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Congenital progressive ataxia and spastic paresis, a hereditary disease in swine, maps to Chromosome 3 by linkage analysis 1 1 1 1 1 2 3 4 A. Kratzsch, C. Stricker, C. Gmu ¨r, S. Rieder, H. Jo ¨ rg, P. Ossent, E. Bu ¨ rgi, W. Zimmermann, 1 1 G. Stranzinger, P. Vo ¨ geli Institute of Animal Sciences, ETH-Zentrum, CH-8092 Zurich, Switzerland Institute of Veterinary Pathology, University of Zurich, CH-8057 Zurich, Switzerland Department of Veterinary Internal Medicine, University of Zurich, CH-8057 Zurich, Switzerland Swine Health Service, University of Berne, CH-3012 Berne, Switzerland Received: 22 February 1999 / Accepted: 4 June 1999 The congenital progressive ataxia (CPA) and spastic paresis in luted samples were analyzed on a 373A ABI Sequencer (Applied pigs, recently identified in Switzerland, is a disease with unknown Biosystems Inc.). Linkage analysis was carried out with the CRI- etiology. A disease similar to CPA was described earlier by Ri- MAP program, version 2.4 (Green et al. 1990). maila-Pa ¨rna ¨nen (1982). The affected animals show a neuropathic In the inbreeding scheme among the phenotypically normal disorder, which occurs in piglets of both
Mammalian Genome – Springer Journals
Published: Oct 1, 1999
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