Tech Coloproctol (2017) 21:531–540 DOI 10.1007/s10151-017-1654-4 ORIGINAL ARTICLE Confocal laser endomicroscopy in ulcerative colitis: beyond endoscopic assessment of disease activity 1 1 1 1 2 • • • • • F. Maione M. C. Giglio G. Luglio A. Rispo M. D’Armiento 1 1 1 1 1 • • • • • B. Manzo G. Cassese P. Schettino N. Gennarelli S. Siciliano 2 1 F. P. D’Armiento G. D. De Palma Received: 14 August 2016 / Accepted: 25 February 2017 / Published online: 3 July 2017 Springer International Publishing AG 2017 Abstract identiﬁed in about 20% of UC patients with normal Background The aim of this study was to investigate the mucosa. Biopsies also demonstrated the presence of his- role of confocal laser endomicroscopy (CLE) in the tological activity in 4 patients with endoscopically inactive assessment of disease activity in ulcerative colitis (UC). colitis. Methods Consecutive patients with UC referred to our Conclusions CLE might be a useful tool to determine inﬂammatory bowel disease unit for colonoscopy were inﬂammatory activity in UC. Fused crypts appeared to be a enrolled. Patients without UC were used as controls. UC CLE marker of UC, while other abnormalities, like activity was evaluated by white
Techniques in Coloproctology – Springer Journals
Published: Jul 3, 2017
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