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P. Salmela, K. Belák, D. Gavier-Widén (1993)
The Occurrence of European Brown Hare Syndrome in FinlandActa Veterinaria Scandinavica, 34
D. Chasey, P. Duff (1990)
European brown hare syndrome and associated virus particles in the UKVeterinary Record, 126
J. Abrantes, W. Loo, J. Pendu, P. Esteves (2012)
Rabbit haemorrhagic disease (RHD) and rabbit haemorrhagic disease virus (RHDV): a reviewVeterinary Research, 43
D. Gavier-Widén, T. Mörner (1991)
Epidemiology and diagnosis of the European brown hare syndrome in Scandinavian countries: a review.Revue scientifique et technique, 10 2
G. Gall, S. Huguet, P. Vende, J. Vautherot, D. Rasschaert (1996)
European brown hare syndrome virus: molecular cloning and sequencing of the genome.The Journal of general virology, 77 ( Pt 8)
C. Bascuñana, Norbert Nowotny, Sándor Belák (1997)
Detection and differentiation of rabbit hemorrhagic disease and European brown hare syndrome viruses by amplification of VP60 genomic sequences from fresh and fixed tissue specimensJournal of Clinical Microbiology, 35
K. Frölich, J. Fickel, A. Ludwig, D. Lieckfeldt, W. Streich, R. Jurčík, J. Slamecka, G. Wibbelt (2007)
NEW VARIANTS OF EUROPEAN BROWN HARE SYNDROME VIRUS STRAINS IN FREE-RANGING EUROPEAN BROWN HARES (LEPUS EUROPAEUS) FROM SLOVAKIA, 43
Christoph Wirblich, M. Sibilia, M. Boniotti, C. Rossi, Heinz-Jürgen Thiel, G. Meyers (1995)
3C-like protease of rabbit hemorrhagic disease virus: identification of cleavage sites in the ORF1 polyprotein and analysis of cleavage specificityJournal of Virology, 69
Acknowledgments The Portuguese Foundation for Science and Technology (FCT) supported the doctoral fellowship of Ana M
E. Williams, I. Barker (2001)
Infectious diseases of wild mammals.
J. Abrantes, P. Esteves, W. Loo (2008)
Evidence for recombination in the major capsid gene VP60 of the rabbit haemorrhagic disease virus (RHDV)Archives of Virology, 153
D. Gavier-Widén (1994)
Morphologic and Immunohistochemical Characterization of the Hepatic Lesions Associated with European Brown Hare SyndromeVeterinary Pathology, 31
Christoph Wirblich, G. Meyers, V. Ohlinger, Lorenzo Capucci, U. Eskens, B. Haas, Heinz-Jürgen Thiel (1994)
European brown hare syndrome virus: relationship to rabbit hemorrhagic disease virus and other calicivirusesJournal of Virology, 68
K. Frölich, G. Haerer, L. Bacciarini, M. Janovský, Michael Rudolph, M. Giacometti (2001)
European Brown Hare Syndrome in Free-ranging European Brown and Mountain Hares from Switzerland, 37
H.CH. Loliger, U. Eskens (1991)
Incidence, epizootiology and control of viral haemorrhagic disease of rabbits and the European brown hare syndrome in Germany.Revue scientifique et technique, 10 2
(2008)
The FCT Project PTDC/ CVT
C. Billinis, V. Psychas, D. Tontis, V. Spyrou, P. Birtsas, M. Sofia, Fotios Likotrafitis, O. Maslarinou, D. Kanteres (2005)
European Brown Hare Syndrome in Wild European Brown Hares from Greece, 41
G. Meyers, Christoph Wirblich, Heinz-Jürgen Thiel, Jörg Thumfart (2000)
Rabbit hemorrhagic disease virus: genome organization and polyprotein processing of a calicivirus studied after transient expression of cDNA constructs.Virology, 276 2
G. Gall-Reculé, F. Zwingelstein, S. Laurent, Y. Portejoie, D. Rasschaert (2006)
Molecular epidemiology of European brown hare syndrome virus in France between 1989 and 2003Archives of Virology, 151
N. Macleod, A. Greig, P. Nettleton (1992)
Suspected European brown hare syndrome in ScotlandVeterinary Record, 130
Kai Frandölich, Olgierd Kujawski, M. Rudolph, L. Rønsholt, S. Speck (2003)
EUROPEAN BROWN HARE SYNDROME VIRUS IN FREE-RANGING EUROPEAN BROWN HARES FROM ARGENTINA, 39
Cancellotti Fm, M. Renzi (1991)
Epidemiology and current situation of viral haemorrhagic disease of rabbits and the European brown hare syndrome in Italy.Revue scientifique et technique, 10 2
B. Drews, C. Szentiks, K. Roellig, J. Fickel, K. Schroeder, J. Duff, A. Lavazza, Thomas Hildebrandt, F. Goeritz (2011)
Epidemiology, control and management of an EBHS outbreak in captive hares.Veterinary microbiology, 154 1-2
Naomi Forrester, S. Moss, Sarah Turner, H. Schirrmeier, E. Gould (2008)
Recombination in rabbit haemorrhagic disease virus: possible impact on evolution and epidemiology.Virology, 376 2
J. Duff, D. Chasey, R. Munro, M. Wooldridge (1994)
European brown hare syndrome in EnglandVeterinary Record, 134
K. Frölich, H. Meyer, Z. Pielowski, L. Rønsholt, S. Seck-Lanzendorf, M. Stolte (1996)
EUROPEAN BROWN HARE SYNDROME IN FREE-RANGING HARES IN POLAND, 32
European brown hare syndrome (EBHS) is characterised by high mortality of European brown hares ( Lepus europaeus ) and mountain hares ( Lepus timidus ). European brown hare syndrome virus (EBHSV) and the closely related rabbit haemorrhagic disease virus (RHDV) comprise the genus Lagovirus , family Caliciviridae. In contrast to RHDV, which is well studied, with more than 30 complete genome sequences available, the only complete genome sequence available for EBHSV was obtained from a strain isolated in 1989 in France. EBHS was originally diagnosed in Sweden in 1980. Here, we report the complete coding sequences of two EBHSV strains isolated from European brown hares that died with liver lesions characteristic of EBHS in Sweden in 1982. These sequences represent the oldest complete coding sequences of EBHSV isolated from the original area of virus diagnosis. The genomic organisation is similar to that of the published French sequence. Comparison with this sequence revealed several nucleotide substitutions, corresponding to 6 % divergence. At the amino acid level, the Swedish strains are 2 % different from the French strain. Most amino acid substitutions were located within the major capsid protein VP60, but when considering the amino acid sequence length of each protein, VP10 is the protein with the highest percentage of amino acid differences. The same result was obtained when Swedish strains were compared. This evolutionary pattern has not been described previously for members of the genus Lagovirus .
Archives of Virology – Springer Journals
Published: Oct 1, 2013
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