Mammalian Genome 8, 589-591 (1997). =~rellOllle 9 Springer-Verlag New York Inc. 1997 Comparison of genetic variability at microsatellite loci in wild rats and inbred rat strains (Rattus norvegicus) Ingrid Kliiting, Birger Voigt, Peter Kovacs Department of Laboratory Animal Science, Institute of Pathophysiology, University of Greifswald, Greifswalder Str. 11A, D-17495 Karlsburg, Germany Received: 20 November 1997 / Accepted: 4 April 1997 Mylclv, Ace, II-4, Aep, Sa, Tilp loci. In addition, there were 11 loci Genetic polymorphism of the major histocompatibility complex at which not all known alleles of inbred rats were detected. Four (Cramer et al. 1988; Giinther 1979) and of some classical bio- alleles of those were not found at Planh, three at Cat, two at lg,~2, chemical markers (Bender et al. 1985; Cramer et at. 1988; Erikk- Pbpc2, Afp, and one at D4Mit6, Abp, D18Mit9, Ampp, Tryl, lgfl son et al. 1976; Yamada et at. 1993) has been studied in wild rats. loci. The frequency of new alleles in the wild rats varied from 5 to However, the overall degree of genetic variability in wild rat popu- 100% per locus. The frequency of most of these new alleles was lations remains unclear. This prompted us to analyze 11
Mammalian Genome – Springer Journals
Published: Apr 1, 2009
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