J Cancer Res Clin Oncol (2017) 143:1627–1635 DOI 10.1007/s00432-017-2391-9 REVIEW – CANCER RESEARCH Comparison of dermoscopy and reflectance confocal microscopy for the diagnosis of malignant skin tumours: a meta-analysis 1 2 1 1 1 Yi-Quan Xiong · Shu-Juan Ma · Yun Mo · Shu-Ting Huo · Yu-Qi Wen · Qing Chen Received: 14 February 2017 / Accepted: 27 February 2017 / Published online: 13 March 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract The pooled sensitivity and specificity of RCM were 93.5% Purpose Dermoscopy and reflectance confocal micros- (95% CI 0.90–0.96) and 78.8% (95% CI 0.75–0.82), copy (RCM) are non-invasive methods for diagnosis of respectively. malignant skin tumours. The aim of this study was to com- Conclusions When compared with dermoscopy, RCM pare the accuracy of dermoscopy and RCM for the diagno- has a significantly greater diagnostic specificity for malig- sis of malignant skin tumours. nant skin tumours and so could improve their detection Methods Systematic electronic literature searches were rate. conducted to include PubMed, Medline, Embase, the Cochrane Library database, and Web of Science, up to 26 Keywords Skin cancer · Melanoma · Dermoscopy · April 2016. Pooled additional detection rate (ADR), diag- Reflectance confocal microscopy · Meta-analysis nostic accuracy, and 95% confidence intervals (CIs) were calculated using STATA and Meta-Disc analysis. Results Eight
Journal of Cancer Research and Clinical Oncology – Springer Journals
Published: Mar 13, 2017
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