Comparison of 10- and 20-min hepatobiliary phase images on Gd-EOB-DTPA-enhanced MRI T1 mapping for liver function assessment in clinic

Comparison of 10- and 20-min hepatobiliary phase images on Gd-EOB-DTPA-enhanced MRI T1 mapping... option for quantitatively assessing liver function. Purpose: To compare hepatobiliary phase (HBP) images obtained 10 and 20 min after Gd-EOB-DTPA-enhanced Key words: Liver function—Gd-EOB- MRI for liver function assessment in clinic on 3.0 T MR DTPA—Hepatobiliary phase—MRI—T1 mapping imaging. Methods: 103 patients were separated into four groups: 38 patients for the normal liver function (NLF) group, 33 Abbreviations patients for the liver cirrhosis with Child–Pugh A (LCA) AUC Area under the curve group, 21 patients for the liver cirrhosis with Child–Pugh CNR Contrast-to-noise ratio B group, and 11 patients for a liver cirrhosis with Child– Gd-EOB-DTPA Gadolinium ethoxybenzyl Pugh C group. T1 relaxation times (T1rt) were measured diethylenetriamine pentaacetic acid on T1 mapping and reduction rates of T1rt (rrT1rt) were HBP Hepatobiliary phase calculated. HBP images were obtained at the 10- and MRI Magnetic resonance imaging 20-min mark after Gd-EOB-DTPA enhancement. MELD Model for end-stage liver disease Results: T1rt on pre-enhancement imaging showed no ROC Receiver operating characteristic significant difference (p > 0.05) among all four groups. ROI Region of interest T1rt for both the 10-min HBP and the 20-min HBP rrT1rt Reduction rate of T1 relaxation time showed a significant difference (p < 0.05) among all SI Signal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Abdominal Radiology Springer Journals

Comparison of 10- and 20-min hepatobiliary phase images on Gd-EOB-DTPA-enhanced MRI T1 mapping for liver function assessment in clinic

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Imaging / Radiology; Gastroenterology; Hepatology
ISSN
2366-004X
eISSN
2366-0058
D.O.I.
10.1007/s00261-017-1143-2
Publisher site
See Article on Publisher Site

Abstract

option for quantitatively assessing liver function. Purpose: To compare hepatobiliary phase (HBP) images obtained 10 and 20 min after Gd-EOB-DTPA-enhanced Key words: Liver function—Gd-EOB- MRI for liver function assessment in clinic on 3.0 T MR DTPA—Hepatobiliary phase—MRI—T1 mapping imaging. Methods: 103 patients were separated into four groups: 38 patients for the normal liver function (NLF) group, 33 Abbreviations patients for the liver cirrhosis with Child–Pugh A (LCA) AUC Area under the curve group, 21 patients for the liver cirrhosis with Child–Pugh CNR Contrast-to-noise ratio B group, and 11 patients for a liver cirrhosis with Child– Gd-EOB-DTPA Gadolinium ethoxybenzyl Pugh C group. T1 relaxation times (T1rt) were measured diethylenetriamine pentaacetic acid on T1 mapping and reduction rates of T1rt (rrT1rt) were HBP Hepatobiliary phase calculated. HBP images were obtained at the 10- and MRI Magnetic resonance imaging 20-min mark after Gd-EOB-DTPA enhancement. MELD Model for end-stage liver disease Results: T1rt on pre-enhancement imaging showed no ROC Receiver operating characteristic significant difference (p > 0.05) among all four groups. ROI Region of interest T1rt for both the 10-min HBP and the 20-min HBP rrT1rt Reduction rate of T1 relaxation time showed a significant difference (p < 0.05) among all SI Signal

Journal

Abdominal RadiologySpringer Journals

Published: Apr 10, 2017

References

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