option for quantitatively assessing liver function. Purpose: To compare hepatobiliary phase (HBP) images obtained 10 and 20 min after Gd-EOB-DTPA-enhanced Key words: Liver function—Gd-EOB- MRI for liver function assessment in clinic on 3.0 T MR DTPA—Hepatobiliary phase—MRI—T1 mapping imaging. Methods: 103 patients were separated into four groups: 38 patients for the normal liver function (NLF) group, 33 Abbreviations patients for the liver cirrhosis with Child–Pugh A (LCA) AUC Area under the curve group, 21 patients for the liver cirrhosis with Child–Pugh CNR Contrast-to-noise ratio B group, and 11 patients for a liver cirrhosis with Child– Gd-EOB-DTPA Gadolinium ethoxybenzyl Pugh C group. T1 relaxation times (T1rt) were measured diethylenetriamine pentaacetic acid on T1 mapping and reduction rates of T1rt (rrT1rt) were HBP Hepatobiliary phase calculated. HBP images were obtained at the 10- and MRI Magnetic resonance imaging 20-min mark after Gd-EOB-DTPA enhancement. MELD Model for end-stage liver disease Results: T1rt on pre-enhancement imaging showed no ROC Receiver operating characteristic significant difference (p > 0.05) among all four groups. ROI Region of interest T1rt for both the 10-min HBP and the 20-min HBP rrT1rt Reduction rate of T1 relaxation time showed a significant difference (p < 0.05) among all SI Signal
Abdominal Radiology – Springer Journals
Published: Apr 10, 2017
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