Comparing the Vitex-castus extract and cabergoline effects on estrous induction in female dogs

Comparing the Vitex-castus extract and cabergoline effects on estrous induction in female dogs Cabergoline is used to induce estrus, stop lactation, and induce abortion in small animals. The specific doses of Vitagnus extract have almost identical properties of cabergoline that reduce prolactin and increase the concentration of FSH hormone. The aim of this study was to compare the effect of Vitex agnus-castus extract and cabergoline on prolactin concentration and hormonal changes associated with the onset of estrous cycle in dogs. Twelve healthy adult cyclic female-mix breed dogs were selected and randomly aligned in treatment (6 dogs, Vitagnus extract 1.5 ml daily for 5 weeks, 80–90 mg/ml, PO) and control groups (6 dogs, cabergoline, daily for 5 weeks, 5 μg/kg, PO). Blood sampling and vaginal smears were taken weekly. Serum samples were stored at −20 °C until prolactin, estradiol, and progesterone were measured by ELISA method. Based on vaginal cytology results, four (cabergoline) and three (Vitagnus) dogs were in the estrous phase after 5 weeks of treatment. The average concentration of the prolactin was not changed during 5 weeks and between two groups. There was no significant difference in progesterone and estradiol levels between groups. The changes of estradiol concentration were significant during the 5 weeks (p < 0.01). The mean concentration of this hormone changed significantly between weeks 2 and 3 (p < 0.01), 2 and 5 (p < 0.05), and 3 and 4 (p < 0.05). In conclusion, Vitagnus extract had hormonal effects similar to those of cabergoline for induction of estrus in bitches. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Comparative Clinical Pathology Springer Journals

Comparing the Vitex-castus extract and cabergoline effects on estrous induction in female dogs

Loading next page...
 
/lp/springer_journal/comparing-the-vitex-castus-extract-and-cabergoline-effects-on-estrous-iowO00ZGC6
Publisher
Springer London
Copyright
Copyright © 2017 by Springer-Verlag London
Subject
Medicine & Public Health; Pathology; Hematology; Oncology
eISSN
1618-565X
D.O.I.
10.1007/s00580-017-2491-6
Publisher site
See Article on Publisher Site

Abstract

Cabergoline is used to induce estrus, stop lactation, and induce abortion in small animals. The specific doses of Vitagnus extract have almost identical properties of cabergoline that reduce prolactin and increase the concentration of FSH hormone. The aim of this study was to compare the effect of Vitex agnus-castus extract and cabergoline on prolactin concentration and hormonal changes associated with the onset of estrous cycle in dogs. Twelve healthy adult cyclic female-mix breed dogs were selected and randomly aligned in treatment (6 dogs, Vitagnus extract 1.5 ml daily for 5 weeks, 80–90 mg/ml, PO) and control groups (6 dogs, cabergoline, daily for 5 weeks, 5 μg/kg, PO). Blood sampling and vaginal smears were taken weekly. Serum samples were stored at −20 °C until prolactin, estradiol, and progesterone were measured by ELISA method. Based on vaginal cytology results, four (cabergoline) and three (Vitagnus) dogs were in the estrous phase after 5 weeks of treatment. The average concentration of the prolactin was not changed during 5 weeks and between two groups. There was no significant difference in progesterone and estradiol levels between groups. The changes of estradiol concentration were significant during the 5 weeks (p < 0.01). The mean concentration of this hormone changed significantly between weeks 2 and 3 (p < 0.01), 2 and 5 (p < 0.05), and 3 and 4 (p < 0.05). In conclusion, Vitagnus extract had hormonal effects similar to those of cabergoline for induction of estrus in bitches.

Journal

Comparative Clinical PathologySpringer Journals

Published: May 21, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off