Comparative efficacy and safety of tacrolimus, mycophenolate mofetil, azathioprine, and cyclophosphamide as maintenance therapy for lupus nephritis

Comparative efficacy and safety of tacrolimus, mycophenolate mofetil, azathioprine, and... Originalien Z Rheumatol 2017 · 76:904–912 Y. H. Lee · G. G. Song DOI 10.1007/s00393-016-0186-z Division of Rheumatology, Department of Internal Medicine, Korea University Anam Hospital, Korea Published online: 8 September 2016 University College of Medicine, Seoul, Korea © Springer-Verlag Berlin Heidelberg 2016 Redaktion U. Müller-Ladner, Bad Nauheim Comparative efficacy and safety U. Lange, Bad Nauheim of tacrolimus, mycophenolate mofetil, azathioprine, and cyclophosphamide as maintenance therapy for lupus nephritis A Bayesian network meta-analysis of randomized controlled trials and ovarian toxicity [2]. Other immuno- as maintenance therapy for this indica- Introduction suppressive drugs used for maintenance tion [9]. Evidence from a small number Renal involvement occurs in up to 60 % treatment of lupus nephritis include my- of RCTs comparing the relative efficacy of patients with systemic lupus erythe- cophenolate mofetil (MMF), tacrolimus, and safety of tacrolimus, MMF, AZA, matosus (SLE) and remains a predomi- and azathioprine (AZA). and CYC as maintenance treatment for nant cause of morbidity and mortality in Several meta-analysis studies have lupus nephritis has been inconclusive, SLE [1] The treatment of lupus nephritis attempted to evaluate the efficacy and mainly because of small sample sizes. consists of an induction phase to produce safety of tacrolimus, MMF, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Zeitschrift für Rheumatologie Springer Journals

Comparative efficacy and safety of tacrolimus, mycophenolate mofetil, azathioprine, and cyclophosphamide as maintenance therapy for lupus nephritis

Loading next page...
 
/lp/springer_journal/comparative-efficacy-and-safety-of-tacrolimus-mycophenolate-mofetil-x85zqogPfR
Publisher
Springer Journals
Copyright
Copyright © 2016 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Internal Medicine; Rheumatology
ISSN
0340-1855
eISSN
1435-1250
D.O.I.
10.1007/s00393-016-0186-z
Publisher site
See Article on Publisher Site

Abstract

Originalien Z Rheumatol 2017 · 76:904–912 Y. H. Lee · G. G. Song DOI 10.1007/s00393-016-0186-z Division of Rheumatology, Department of Internal Medicine, Korea University Anam Hospital, Korea Published online: 8 September 2016 University College of Medicine, Seoul, Korea © Springer-Verlag Berlin Heidelberg 2016 Redaktion U. Müller-Ladner, Bad Nauheim Comparative efficacy and safety U. Lange, Bad Nauheim of tacrolimus, mycophenolate mofetil, azathioprine, and cyclophosphamide as maintenance therapy for lupus nephritis A Bayesian network meta-analysis of randomized controlled trials and ovarian toxicity [2]. Other immuno- as maintenance therapy for this indica- Introduction suppressive drugs used for maintenance tion [9]. Evidence from a small number Renal involvement occurs in up to 60 % treatment of lupus nephritis include my- of RCTs comparing the relative efficacy of patients with systemic lupus erythe- cophenolate mofetil (MMF), tacrolimus, and safety of tacrolimus, MMF, AZA, matosus (SLE) and remains a predomi- and azathioprine (AZA). and CYC as maintenance treatment for nant cause of morbidity and mortality in Several meta-analysis studies have lupus nephritis has been inconclusive, SLE [1] The treatment of lupus nephritis attempted to evaluate the efficacy and mainly because of small sample sizes. consists of an induction phase to produce safety of tacrolimus, MMF,

Journal

Zeitschrift für RheumatologieSpringer Journals

Published: Sep 8, 2016

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off