Gastric Cancer (2017) 20:811–824 DOI 10.1007/s10120-017-0693-x ORIGINAL ARTICLE Comparative effectiveness of adjuvant chemoradiotherapy after gastrectomy among older patients with gastric adenocarcinoma: a SEER–Medicare study 1,2 3 3 4 • • • Jennifer M. Yeh Angela C. Tramontano Chin Hur Deborah Schrag Received: 22 December 2016 / Accepted: 14 January 2017 / Published online: 15 February 2017 The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2017 Abstract Results Of the 1519 patients who underwent gastrectomy, Background Since the INT-0116 trial reported a survival 41.7% received adjuvant CRT. Factors associated with advantage, postoperative chemoradiotherapy (CRT) has adjuvant CRT included age younger than 75 years at can- been a care standard for US patients in whom gastric cer diagnosis and stage II or stage III cancer. The median adenocarcinoma has been diagnosed. We sought to esti- overall survival from the time of gastrectomy was mate the association between treatment and survival among 25.1 months (interquartile range 43.7 months) for gas- the older US Medicare population. trectomy only and 26.9 months (interquartile range Methods This is a retrospective cohort study of Medicare 40.9 months) for adjuvant CRT. Multivariable and beneﬁciaries aged 65–79 years with stage IB–III gastric propensity-score-stratiﬁed models demonstrated
Gastric Cancer – Springer Journals
Published: Feb 15, 2017
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