Although equine infectious anemia virus (EIAV) poses a major threat to the equine industry worldwide, the molecular epidemiology of this virus is poorly understood. Recently, an EIAV strain (EIAV Miyazaki2011-A ) representing a new monophyletic group was discovered in feral horses in southern Japan. In the present study, the EIAV Miyazaki2011-A proviral genome is compared with evolutionarily divergent EIAV isolates to investigate conservation of functional elements or motifs within the long terminal repeats (LTRs) and structural genes. This analysis represents a significant step forward in increasing understanding of the molecular conservation and variation between geographically distinct strains of this equine lentivirus.
Archives of Virology – Springer Journals
Published: Dec 1, 2014
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