Cobimetinib
Abstract
Reactions 1704, p117 - 2 Jun 2018 Focal necrotising myopathy with dropped-head syndrome: case report A 72-year-old man developed focal necrotising myopathy with dropped-head syndrome following treatment with cobimetinib [route not stated]. The man, who had Parkinson’s disease and NRAS-mutated advanced melanoma, started receiving treatment with cobimetinib 60 mg/day, 3 weeks and 1 week off. His concurrent treatment included nivolumab, levodopa, unspecified monoamine oxidase inhibitor and...