Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Clusters of genetic diseases in Brazil

Clusters of genetic diseases in Brazil The aim of this paper is to present a database of isolated communities (CENISO) with high prevalence of genetic disorders or congenital anomalies in Brazil. We used two strategies to identify such communities: (1) a systematic literature review and (2) a “rumor strategy” based on anecdotal accounts. All rumors and reports were validated in a stepwise process. The bibliographical search identified 34 rumors and 245 rumors through the rumor strategy, and 144 were confirmed. A database like this one presented here represents an important tool for the planning of health priorities for rare diseases in low- and middle-income countries with large populations. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Community Genetics Springer Journals

Loading next page...
1
 
/lp/springer_journal/clusters-of-genetic-diseases-in-brazil-W5YFB4OJQv

References (35)

Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Biomedicine; Human Genetics; Public Health; Epidemiology; Gene Therapy; Gene Function
ISSN
1868-310X
eISSN
1868-6001
DOI
10.1007/s12687-018-0369-1
Publisher site
See Article on Publisher Site

Abstract

The aim of this paper is to present a database of isolated communities (CENISO) with high prevalence of genetic disorders or congenital anomalies in Brazil. We used two strategies to identify such communities: (1) a systematic literature review and (2) a “rumor strategy” based on anecdotal accounts. All rumors and reports were validated in a stepwise process. The bibliographical search identified 34 rumors and 245 rumors through the rumor strategy, and 144 were confirmed. A database like this one presented here represents an important tool for the planning of health priorities for rare diseases in low- and middle-income countries with large populations.

Journal

Journal of Community GeneticsSpringer Journals

Published: Jun 2, 2018

There are no references for this article.