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Clozapine

Clozapine Reactions 1680, p95 - 2 Dec 2017 Neutropenia: case report A 49-year-old woman developed neutropenia during treatment with clozapine for schizoaffective disorder. The woman had been undergoing treatment with clozapine 600mg daily [route not stated]. Subsequently, she developed moderate neutropenia [duration of treatment to reaction onset and outcome not stated]. Her clozapine was discontinued, however, clozapine 300mg was re-initiated for five months, along with olanzapine and lithium. An analysis of the relation between clozapine and neutropenia by white blood cell (WBC)/absolute neutrophil count (ANC) values did not yield results. Author comment: "[W]e attempt to assess whether a similar relationship exists between clozapine and its hematological side effects (neutropenia/agranulocytosis)." Boazak M, et al. A case report and literature review of clozapine re-challenge titration schedules. CNS Spectrums 22: 87 abstr. 144, No. 1, Feb 2017. Available from: URL: http://doi.org/10.1017/S1092852916000900 [abstract] - USA 803284812 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Clozapine

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Clozapine

Abstract

Reactions 1680, p95 - 2 Dec 2017 Neutropenia: case report A 49-year-old woman developed neutropenia during treatment with clozapine for schizoaffective disorder. The woman had been undergoing treatment with clozapine 600mg daily [route not stated]. Subsequently, she developed moderate neutropenia [duration of treatment to reaction onset and outcome not stated]. Her clozapine was discontinued, however, clozapine 300mg was re-initiated for five months, along with olanzapine and lithium. An...
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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
DOI
10.1007/s40278-017-39026-9
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p95 - 2 Dec 2017 Neutropenia: case report A 49-year-old woman developed neutropenia during treatment with clozapine for schizoaffective disorder. The woman had been undergoing treatment with clozapine 600mg daily [route not stated]. Subsequently, she developed moderate neutropenia [duration of treatment to reaction onset and outcome not stated]. Her clozapine was discontinued, however, clozapine 300mg was re-initiated for five months, along with olanzapine and lithium. An analysis of the relation between clozapine and neutropenia by white blood cell (WBC)/absolute neutrophil count (ANC) values did not yield results. Author comment: "[W]e attempt to assess whether a similar relationship exists between clozapine and its hematological side effects (neutropenia/agranulocytosis)." Boazak M, et al. A case report and literature review of clozapine re-challenge titration schedules. CNS Spectrums 22: 87 abstr. 144, No. 1, Feb 2017. Available from: URL: http://doi.org/10.1017/S1092852916000900 [abstract] - USA 803284812 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

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Reactions Weekly – Springer Journals

Published: Dec 2, 2017

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