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Clozapine

Clozapine Reactions 1680, p96 - 2 Dec 2017 Sedation: case report A woman in her 60s [exact age at the time of event onset not stated] developed sedation during treatment with clozapine. Later, she died due to asphyxia following choking on a handkerchief. The woman, who had a history of chronic schizophrenic psychosis, was receiving treatment with oral clozapine three tablets of 100mg, and lorazepam. In January 2010, her caregiver found her sitting on a couch and coughing loudly and persistently, with her hands around her neck. She tried to explain the caregiver that she had a handkerchief in her throat and was choking. She had forced the handkerchief down her pharynx to silence the voices of spirits. Her husband attempted to pull the paper handkerchief out of her throat, and called the emergency medical services. Later, she died due to suffocation produced by the handkerchief. The toxicological data revealed that at the time of choking, she was in a state of sedation, which was considered secondary to the use of clozapine. Further it was considered that, the state of sedation reduced her capacity to defend herself and possibly develop self-rescue manoeuvres. It was not confirmed that, the woman inserted http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Clozapine

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Clozapine

Abstract

Reactions 1680, p96 - 2 Dec 2017 Sedation: case report A woman in her 60s [exact age at the time of event onset not stated] developed sedation during treatment with clozapine. Later, she died due to asphyxia following choking on a handkerchief. The woman, who had a history of chronic schizophrenic psychosis, was receiving treatment with oral clozapine three tablets of 100mg, and lorazepam. In January 2010, her caregiver found her sitting on a couch and coughing loudly and persistently, with...
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References (1)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
DOI
10.1007/s40278-017-39027-9
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p96 - 2 Dec 2017 Sedation: case report A woman in her 60s [exact age at the time of event onset not stated] developed sedation during treatment with clozapine. Later, she died due to asphyxia following choking on a handkerchief. The woman, who had a history of chronic schizophrenic psychosis, was receiving treatment with oral clozapine three tablets of 100mg, and lorazepam. In January 2010, her caregiver found her sitting on a couch and coughing loudly and persistently, with her hands around her neck. She tried to explain the caregiver that she had a handkerchief in her throat and was choking. She had forced the handkerchief down her pharynx to silence the voices of spirits. Her husband attempted to pull the paper handkerchief out of her throat, and called the emergency medical services. Later, she died due to suffocation produced by the handkerchief. The toxicological data revealed that at the time of choking, she was in a state of sedation, which was considered secondary to the use of clozapine. Further it was considered that, the state of sedation reduced her capacity to defend herself and possibly develop self-rescue manoeuvres. It was not confirmed that, the woman inserted

Journal

Reactions Weekly – Springer Journals

Published: Dec 2, 2017

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