Cloning, expression, and promoter structure of a mammalian Inner Centromere Protein (INCENP)

Cloning, expression, and promoter structure of a mammalian Inner Centromere Protein (INCENP) Mammalian Genome 10, 415–418 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Cloning, expression, and promoter structure of a mammalian Inner Centromere Protein (INCENP) Richard Saffery, Danielle V. Irvine, Benjamin T. Kile, Damien F. Hudson, Suzanne M. Cutts, K.H. Andy Choo The Murdoch Institute, Royal Children’s Hospital, Flemington Road, Parkville, 3052, Victoria, Australia Received: 28 September 1998 / Accepted: 2 December 1998 The term ‘chromosomal passenger proteins’ was first coined to cDNA revealed the presence of 3 Cdc2 kinase sites and 3 MAP describe a group of cellular proteins that tightly associate with kinase sites within the Xenopus protein (Stukenburg et al. 1997). chromosomes during the early stages of mitosis, localize at the To date, no mammalian homolog of INCENP has been de- centromere at metaphase, and subsequently relocate to other sub- scribed. This report describes the cloning, sequencing, tissue ex- cellular regions at the commencement of anaphase (Earnshaw and pression, and promoter analysis of mouse INCENP. Bernat 1990). One of these proteins, the Inner Centromere Protein BLAST searches were carried out using chicken INCENP se- or INCENP, was first identified using antibodies raised against quences against the EST database. Several mouse EST clones with chicken chromosomal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Cloning, expression, and promoter structure of a mammalian Inner Centromere Protein (INCENP)

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Publisher
Springer-Verlag
Copyright
Copyright © 1999 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359901014
Publisher site
See Article on Publisher Site

Abstract

Mammalian Genome 10, 415–418 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Cloning, expression, and promoter structure of a mammalian Inner Centromere Protein (INCENP) Richard Saffery, Danielle V. Irvine, Benjamin T. Kile, Damien F. Hudson, Suzanne M. Cutts, K.H. Andy Choo The Murdoch Institute, Royal Children’s Hospital, Flemington Road, Parkville, 3052, Victoria, Australia Received: 28 September 1998 / Accepted: 2 December 1998 The term ‘chromosomal passenger proteins’ was first coined to cDNA revealed the presence of 3 Cdc2 kinase sites and 3 MAP describe a group of cellular proteins that tightly associate with kinase sites within the Xenopus protein (Stukenburg et al. 1997). chromosomes during the early stages of mitosis, localize at the To date, no mammalian homolog of INCENP has been de- centromere at metaphase, and subsequently relocate to other sub- scribed. This report describes the cloning, sequencing, tissue ex- cellular regions at the commencement of anaphase (Earnshaw and pression, and promoter analysis of mouse INCENP. Bernat 1990). One of these proteins, the Inner Centromere Protein BLAST searches were carried out using chicken INCENP se- or INCENP, was first identified using antibodies raised against quences against the EST database. Several mouse EST clones with chicken chromosomal

Journal

Mammalian GenomeSpringer Journals

Published: Apr 1, 1999

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