J Endocrinol Invest (2018) 41:403–409 https://doi.org/10.1007/s40618-017-0759-y ORIGINAL ARTICLE Clinical and pathologic predictors of central lymph node metastasis in papillary thyroid microcarcinoma: a retrospective cohort study 1 2 2 2 C. Y. Gui · S. L. Qiu · Z. H. Peng · M. Wang Received: 12 June 2017 / Accepted: 26 August 2017 / Published online: 7 September 2017 © Italian Society of Endocrinology (SIE) 2017 Abstract Conclusions A relatively high prevalence of CLNM was Objective To identify the clinical and pathological predic- observed in patients with clinically lymph node-negative tors of central lymph node metastasis (CLNM) in patients PTMC. CLNM was associated with male sex, younger age, with clinically lymph node-negative papillary thyroid micro- larger tumor size, extrathyroidal extension and multifocal carcinoma (PTMC). PTMC. Materials and methods Data pertaining to 541 clinically lymph node-negative PTMC patients who underwent thyroid Keywords Papillary thyroid microcarcinoma · Central surgery at the Shanghai General Hospital between January lymph node metastasis · Central lymph node dissection 2010 and December 2013 were retrospectively analyzed. According to histopathological evidence of central lymph node involvement, patients were divided into central lymph Background node metastasis (CLNM)-positive and CLNM-negative groups; risk factors for CLNM were identified statistically. The global incidence of thyroid cancer has seen a dramatic Results LNM was found
Journal of Endocrinological Investigation – Springer Journals
Published: Sep 7, 2017
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