Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2557-0) contains supplementary material, which is available to authorized users. & Appaswami Lalitha email@example.com Department of Chemistry, Periyar University, Periyar Palkalai Nagar, Salem, Tamil Nadu 636011, India Department of Chemistry, Salem Sowdeswari College, Salem, Tamil Nadu 636010, India 123 7626 R. Ramesh et al. Keywords Organocatalysis 2-Aminopyridine Three-component reaction Tetrahydro-4H-chromenes Introduction The progress of expeditious and environmentally benign synthetic protocols that provide diversity oriented ‘‘drug like’’ molecules in a simple synthetic route with interesting properties is a vital aspiration in modern organic chemistry [1–3]. The C–C bond forming base catalyzed condensation as well as some of the addition reactions such as Aldol, Knoevenagel condensations, and Michael reactions, which are used for the commercial production of drugs, fragrances, and various chemical intermediates are industrially more imperative [4–7]. In recent years, exploration of organocatalysis has gained promising signiﬁcance in the ﬁeld of the synthetic community due to its experimental simplicity, metal-free, and non-hazardous treatments [8–10]. Multicomponent reactions (MCRs) are the attractive avenues for the generation of diverse heterocyclic targets in a rapid and efﬁcient manner, because the products can be achieved in one-step processes simply by altering the reacting substrates
Research on Chemical Intermediates – Springer Journals
Published: Apr 30, 2016
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