Reactions 1704, p107 - 2 Jun 2018
Nausea and palpitations: case report
A 78-year-old man developed nausea and palpitations
during treatment with clarithromycin for primary immune
thrombocytopenia [route, duration of treatment to reaction
onsets and outcomes not stated].
The man, who had a history of diabetes mellitus, was
diagnosed with primary immune thrombocytopenia. He
started receiving treatment with clarithromycin 800 mg/day.
After two weeks of treatment with clarithromycin, there was
an improvement in his platelet count. However, he developed
gradual nausea and palpitation secondary to clarithromycin.
The man’s treatment with clarithromycin was discontinued.
He received treatment with prednisolone instead of
clarithromycin. A subsequent improvement in his underlying
condition was noted.
Author comment: "The [clarithromycin] treatment was
terminated owing to gradual nausea and palpitation that are
probably adverse reactions of [clarithromycin]."
Ohe M, et al. Successful treatment of primary immune thrombocytopenia
accompanied by diabetes mellitus treated using clarithromycin followed by
prednisolone. Drug Discoveries and Therapeutics 12: 101-103, No. 2, 2018.
Available from: URL: http://doi.org/10.5582/ddt.2018.01008 - Japan
Reactions 2 Jun 2018 No. 17040114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved