Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with young men and women and positively associated with whole-body bone mineral density in older adults

Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with... Osteoporos Int (2017) 28:2683–2689 DOI 10.1007/s00198-017-4104-2 ORIGINAL ARTICLE Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with young men and women and positively associated with whole-body bone mineral density in older adults 1 1 1,2 1 3 J. Coulson & L. Bagley & Y. Barnouin & S. Bradburn & G. Butler-Browne & 4 3 5 6,7 8 H. Gapeyeva & J.-Y. Hogrel & T. Maden-Wilkinson & A. B. Maier & C. Meskers & 1 9 4 10 11 1 C. Murgatroyd & M. Narici & M. Pääsuke & L. Sassano & S. Sipilä & N. AL-Shanti & 11,12 1 1 L. Stenroth & D. A. Jones & J. S. McPhee Received: 10 January 2017 /Accepted: 23 May 2017 /Published online: 5 June 2017 International Osteoporosis Foundation and National Osteoporosis Foundation 2017 Abstract subjects (69 to 81 years; 52% female) and 171 younger subjects Summary Bone mineral density declines with increasing older (18–30 years; 53% female). age. We examined the levels of circulating factors known to Results WBMD was lower in old than young. Circulating regulate bone metabolism in healthy young and older adults. osteocalcin was lower in old compared with young, while The circulating levels http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Osteoporosis International Springer Journals

Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with young men and women and positively associated with whole-body bone mineral density in older adults

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Publisher
Springer London
Copyright
Copyright © 2017 by International Osteoporosis Foundation and National Osteoporosis Foundation
Subject
Medicine & Public Health; Orthopedics; Endocrinology; Rheumatology
ISSN
0937-941X
eISSN
1433-2965
D.O.I.
10.1007/s00198-017-4104-2
Publisher site
See Article on Publisher Site

Abstract

Osteoporos Int (2017) 28:2683–2689 DOI 10.1007/s00198-017-4104-2 ORIGINAL ARTICLE Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with young men and women and positively associated with whole-body bone mineral density in older adults 1 1 1,2 1 3 J. Coulson & L. Bagley & Y. Barnouin & S. Bradburn & G. Butler-Browne & 4 3 5 6,7 8 H. Gapeyeva & J.-Y. Hogrel & T. Maden-Wilkinson & A. B. Maier & C. Meskers & 1 9 4 10 11 1 C. Murgatroyd & M. Narici & M. Pääsuke & L. Sassano & S. Sipilä & N. AL-Shanti & 11,12 1 1 L. Stenroth & D. A. Jones & J. S. McPhee Received: 10 January 2017 /Accepted: 23 May 2017 /Published online: 5 June 2017 International Osteoporosis Foundation and National Osteoporosis Foundation 2017 Abstract subjects (69 to 81 years; 52% female) and 171 younger subjects Summary Bone mineral density declines with increasing older (18–30 years; 53% female). age. We examined the levels of circulating factors known to Results WBMD was lower in old than young. Circulating regulate bone metabolism in healthy young and older adults. osteocalcin was lower in old compared with young, while The circulating levels

Journal

Osteoporosis InternationalSpringer Journals

Published: Jun 5, 2017

References

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