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J. Klein (1975)
Biology of the Mouse Histocompatibility-2 Complex
J. Sherrard, D. Green, L. Swinden, M. Dalling (1976)
Identification of wheat (Triticum aestivum L.) chromosomes with genes controlling the level of nitrate reductase, nitrite reductase, and acid proteinase using the Chinese Spring-Hope substitution linesBiochemical Genetics, 14
C. Bryant, H. Chang, J. Zhang, T. Wiltshire, L. Tarantino, A. Palmer (2009)
A major QTL on chromosome 11 influences psychostimulant and opioid sensitivity in miceGenes, 8
J. Heaney, M. Lam, Megan Michelson, J. Nadeau (2008)
Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice.Cancer research, 68 13
P. Jansa, Petr Divina, J. Forejt (2005)
Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain)BMC Genomics, 6
He Yang, Kazuhiro Shimomura, M. Vitaterna, Fred Turek (2012)
High‐resolution mapping of a novel genetic locus regulating voluntary physical activity in miceGenes, 11
S. Gregorová, J. Forejt (2000)
PWD/Ph and PWK/Ph inbred mouse strains of Mus m. musculus subspecies--a valuable resource of phenotypic variations and genomic polymorphisms.Folia biologica, 46 1
V. Grandjean, P. Gounon, N. Wagner, Luc Martin, K. Wagner, F. Bernex, F. Cuzin, M. Rassoulzadegan (2009)
The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growthDevelopment, 136
T. Takada, Akihiko Mita, Akiteru Maeno, Takahiro Sakai, H. Shitara, Y. Kikkawa, K. Moriwaki, H. Yonekawa, T. Shiroishi (2008)
Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits.Genome research, 18 3
J. Suto (2009)
Metabolic consequence of congenital asplenia caused by the Dominant hemimelia mutation in mice.The Journal of veterinary medical science, 71 2
B. Yalcin, Kim Wong, A. Agam, Martin Goodson, Thomas Keane, Xiangchao Gan, C. Nellåker, L. Goodstadt, J. Nicod, A. Bhomra, Polinka Hernandez-Pliego, Helen Whitley, James Cleak, R. Dutton, D. Janowitz, R. Mott, D. Adams, J. Flint (2011)
Sequence-based characterization of structural variation in the mouse genomeNature, 477
A. Oka, Akihiko Mita, Yuki Takada, H. Koseki, T. Shiroishi (2010)
Reproductive Isolation in Hybrid Mice Due to Spermatogenesis Defects at Three Meiotic StagesGenetics, 186
R. Ajioka, R. Leboeuf, R. Gillespie, L. Amon, J. Kushner (2007)
Mapping genes responsible for strain-specific iron phenotypes in murine chromosome substitution strains.Blood cells, molecules & diseases, 39 2
Ian Hines, H. Hartwell, Yan Feng, E. Theve, G. Hall, S. Hashway, Jessica Connolly, Michelle Fecteau, J. Fox, A. Rogers (2011)
Insulin resistance and metabolic hepatocarcinogenesis with parent-of-origin effects in A×B mice.The American journal of pathology, 179 6
C. Barrick, An-ping Dong, R. Waikel, Drew Corn, Fanmuyi Yang, D. Threadgill, S. Smyth (2009)
Parent-of-origin effects on cardiac response to pressure overload in mice.American journal of physiology. Heart and circulatory physiology, 297 3
B. Beutler, E. Moresco (2008)
The forward genetic dissection of afferent innate immunity.Current topics in microbiology and immunology, 321
He Yang, M. Vitaterna, A. Laposky, K. Shimomura, F. Turek (2009)
Genetic analysis of daily physical activity using a mouse chromosome substitution strain.Physiological genomics, 39 1
Haifeng Shao, L. Burrage, D. Sinasac, Annie Hill, Sheila Ernest, William O'Brien, H. Courtland, K. Jepsen, Andrew Kirby, E. Kulbokas, M. Daly, K. Broman, E. Lander, J. Nadeau (2008)
Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasisProceedings of the National Academy of Sciences, 105
T. Dobzhansky, S. Wright (1969)
Evolution and the Genetics of Populations, Vol. 1, Genetic and Biometric FoundationsBioScience
K. Moriwaki, N. Miyashita, Y. Yamaguchi, T. Shiroishi (1999)
Multiple genes governing biological functions in the genetic backgrounds of laboratory mice and Asian wild mice.Progress in experimental tumor research, 35
A. Takahashi, K. Tomihara, T. Shiroishi, Tsuyoshi Koide (2009)
Genetic Mapping of Social Interaction Behavior in B6/MSM Consomic Mouse StrainsBehavior Genetics, 40
J. Nadeau (2001)
Modifier genes in mice and humansNature Reviews Genetics, 2
Stephen Grubb, C. Bult, M. Bogue (2013)
Mouse Phenome DatabaseNucleic Acids Research, 42
A. Mallon, V. Iyer, David Melvin, Hugh Morgan, H. Parkinson, Steve Brown, Paul Flicek, W. Skarnes (2012)
Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plansMammalian Genome, 23
Jeremy Wang, Fernando Villena, Heather Lawson, J. Cheverud, G. Churchill, L. McMillan (2012)
Imputation of Single-Nucleotide Polymorphisms in Inbred Mice Using Local PhylogenyGenetics, 190
F. Probst, M. Justice (2010)
Mouse mutagenesis with the chemical supermutagen ENU.Methods in enzymology, 477
David Aylor, W. Valdar, Wendy Foulds-Mathes, Ryan Buus, R. Verdugo, R. Baric, M. Ferris, J. Frelinger, M. Heise, M. Frieman, Lisa Gralinski, T. Bell, J. Didion, K. Hua, D. Nehrenberg, Christine Powell, Jill Steigerwalt, Yuying Xie, S. Kelada, F. Collins, Ivana Yang, D. Schwartz, Lisa Branstetter, E. Chesler, Darla Miller, J. Spence, E. Liu, L. McMillan, Abhishek Sarkar, Jeremy Wang, Wei Wang, Qi Zhang, K. Broman, R. Korstanje, C. Durrant, R. Mott, F. Iraqi, D. Pomp, D. Threadgill, Fernando Villena, G. Churchill (2011)
Genetic analysis of complex traits in the emerging Collaborative Cross.Genome research, 21 8
Thomas Keane, L. Goodstadt, P. Danecek, Michael White, Kim Wong, B. Yalcin, A. Heger, A. Agam, G. Slater, Martin Goodson, N. Furlotte, E. Eskin, C. Nellåker, Helen Whitley, James Cleak, D. Janowitz, Polinka Hernandez-Pliego, Andrew Edwards, T. Belgard, Peter Oliver, R. McIntyre, A. Bhomra, J. Nicod, Xiangchao Gan, Wei Yuan, L. Weyden, C. Steward, Sendu Bala, J. Stalker, R. Mott, R. Durbin, Ian Jackson, A. Czechanski, J. Guerra-Assunção, Leah Donahue, L. Reinholdt, B. Payseur, C. Ponting, E. Birney, J. Flint, David Adams (2011)
Mouse genomic variation and its effect on phenotypes and gene regulationNature, 477
Jade Hollis-Moffatt, S. Hook, T. Merriman (2005)
Colocalization of mouse autoimmune diabetes loci Idd21.1 and Idd21.2 with IDDM6 (human) and Iddm3 (rat).Diabetes, 54 9
Rui Zhu, J. Heaney, J. Nadeau, Sara Ali, A. Matin (2010)
Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors.Cancer research, 70 18
J. Belknap (2003)
Chromosome substitution strains: some quantitative considerations for genome scans and fine mappingMammalian Genome, 14
J. Nadeau, R. Balling, G. Barsh, D. Beier, S. Brown, M. Bucan, S. Camper, George Carlson, N. Copeland, J. Eppig, C. Fletcher, W. Frankel, D. Ganten, D. Goldowitz, C. Goodnow, J. Guénet, G. Hicks, M. Angelis, I. Jackson, H. Jacob, N. Jenkins, Dabney Johnson, M. Justice, S. Kay, D. Kingsley, H. Lehrach, T. Magnuson, M. Meisler, A. Poustka, E. Rinchik, J. Rossant, L. Russell, J. Schimenti, T. Shiroishi, W. Skarnes, Philippe Soriano, W. Stanford, J. Takahashi, W. Wurst, A. Zimmer (2001)
Functional Annotation of Mouse Genome SequencesScience, 291
K. Frazer, E. Eskin, H. Kang, M. Bogue, D. Hinds, Erica Beilharz, Robert Gupta, J. Montgomery, Matt Morenzoni, Geoffrey Nilsen, C. Pethiyagoda, L. Stuve, F. Johnson, M. Daly, C. Wade, D. Cox (2007)
A sequence-based variation map of 8.27 million SNPs in inbred mouse strainsNature, 448
Philip Anderson, Vicki Nelson, P. Tesar, J. Nadeau (2009)
Genetic factors on mouse chromosome 18 affecting susceptibility to testicular germ cell tumors and permissiveness to embryonic stem cell derivation.Cancer research, 69 23
L. Daxinger, E. Whitelaw (2012)
Understanding transgenerational epigenetic inheritance via the gametes in mammalsNature Reviews Genetics, 13
C. Cooney, A. Dave, G. Wolff (2002)
Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring.The Journal of nutrition, 132 8 Suppl
Sheau-Fang Ng, R. Lin, D. Laybutt, R. Barrès, J. Owens, M. Morris (2010)
Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspringNature, 467
Benjamin Carone, Lucas Fauquier, Naomi Habib, Jeremy Shea, C. Hart, Ruowang Li, C. Bock, Chengjian Li, H. Gu, P. Zamore, A. Meissner, Z. Weng, H. Hofmann, N. Friedman, O. Rando (2010)
Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in MammalsCell, 143
C. Fernandes, Lin Liu, J. Paya-Cano, S. Gregorová, J. Forejt, L. Schalkwyk (2004)
Behavioral Characterization of Wild Derived Male Mice (Mus musculus musculus) of the PWD/Ph Inbred Strain: High Exploration Compared to C57BL/6JBehavior Genetics, 34
S. Jong, M. Kas, J. Kiernan, Annetrude Malsen, H. Oppelaar, Esther Janson, I. Vukobradovic, C. Farber, W. Stanford, R. Ophoff (2011)
Hippocampal Gene Expression Analysis Highlights Ly6a/Sca-1 as Candidate Gene for Previously Mapped Novelty Induced Behaviors in MicePLoS ONE, 6
G. Burgio, M. Szatanik, J. Guénet, M. Arnau, J. Panthier, X. Montagutelli (2007)
Interspecific Recombinant Congenic Strains Between C57BL/6 and Mice of the Mus spretus Species: A Powerful Tool to Dissect Genetic Control of Complex TraitsGenetics, 177
L. Case, Leon Toussaint, Mohamad Moussawi, Brian Roberts, N. Saligrama, L. Brossay, S. Huber, C. Teuscher (2012)
Chromosome Y Regulates Survival Following Murine Coxsackievirus B3 InfectionG3: Genes|Genomes|Genetics, 2
O. Mihola, Z. Trachtulec, Č. Vlček, J. Schimenti, J. Forejt (2009)
A Mouse Speciation Gene Encodes a Meiotic Histone H3 MethyltransferaseScience, 323
Sun-Hee Ahn, H. Deshmukh, Nicole Johnson, L. Cowell, T. Rude, W. Scott, C. Nelson, A. Zaas, D. Marchuk, S. Keum, S. Lamlertthon, Batu Sharma-Kuinkel, G. Sempowski, V. Fowler (2010)
Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL AnalysesPLoS Pathogens, 6
LM Silver (1995)
Mouse Genetics
G. Churchill, D. Gatti, Steven Munger, K. Svenson (2012)
The diversity outbred mouse populationMammalian Genome, 23
A. Hillhouse, M. Myles, Jeremy Taylor, E. Bryda, C. Franklin (2011)
Quantitative trait loci in a bacterially induced model of inflammatory bowel diseaseMammalian Genome, 22
A. Nishi, A. Ishii, A. Takahashi, T. Shiroishi, Tsuyoshi Koide (2010)
QTL analysis of measures of mouse home-cage activity using B6/MSM consomic strainsMammalian Genome, 21
H. Yonekawa, S. Takahama, O. Gotoh, N. Miyashita, K. Moriwaki (1994)
Genetic Diversity and Geographic Distribution of Mus musculus Subspecies Based on the Polymorphism of Mitochondrial DNA
J. Forejt, J. Piálek, Z. Trachtulec (2012)
Evolution of the House Mouse: Hybrid male sterility genes in the mouse subspecific crosses
A. Takahashi, A. Takahashi, A. Nishi, A. Nishi, A. Ishii, A. Ishii, T. Shiroishi, T. Shiroishi, Tsuyoshi Koide, Tsuyoshi Koide (2008)
Systematic analysis of emotionality in consomic mouse strains established from C57BL/6J and wild-derived MSM/MsGenes, Brain, and Behavior, 7
CSSs: gene discovery, functional analysis, systems studies 703
Maria Dzur-Gejdosova, P. Simecek, S. Gregorová, Tanmoy Bhattacharyya, J. Forejt (2012)
DISSECTING THE GENETIC ARCHITECTURE OF F1 HYBRID STERILITY IN HOUSE MICEEvolution, 66
A. Glazier, J. Nadeau, T. Aitman (2002)
Finding Genes That Underlie Complex TraitsScience, 298
Tsuyoshi Koide, K. Moriwaki, K. Ikeda, H. Niki, T. Shiroishi (2000)
Multi-phenotype behavioral characterization of inbred strains derived from wild stocks of Mus musculusMammalian Genome, 11
C. Alabert, Anja Groth (2012)
Chromatin replication and epigenome maintenanceNature Reviews Molecular Cell Biology, 13
K. Roberts, V. Abraira, Andrew Tucker, L. Goodrich, N. Andrews (2012)
Mutation of Rubie, a Novel Long Non-Coding RNA Located Upstream of Bmp4, Causes Vestibular Malformation in MicePLoS ONE, 7
Vicki Nelson, J. Nadeau (2010)
Transgenerational genetic effects.Epigenomics, 2 6
E. Hessel, K. Gassen, I. Wolterink‐Donselaar, P. Stienen, C. Fernandes, J. Brakkee, M. Kas, P. Graan (2009)
Phenotyping mouse chromosome substitution strains reveal multiple QTLs for febrile seizure susceptibilityGenes, 8
J Lipid Res
A Oka, T Shiroishi (2012)
Evolution of the House Mouse, Cambridge Series in Morphology and Molecules: New Paradigms in Evolutionary Biology
Y. Ochiai, Y. Tamura, Yuko Saito, A. Matsuki, Y. Wakabayashi, Y. Aizawa, O. Niwa, R. Kominami (2003)
Mapping of genetic modifiers of thymic lymphoma development in p53-knockout miceOncogene, 22
K. Wagner, N. Wagner, H. Ghanbarian, V. Grandjean, P. Gounon, F. Cuzin, M. Rassoulzadegan (2008)
RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse.Developmental cell, 14 6
Haifeng Shao, D. Sinasac, L. Burrage, C. Hodges, Pamela Supelak, M. Palmert, Carol Moreno, A. Cowley, H. Jacob, J. Nadeau (2010)
Analyzing complex traits with congenic strainsMammalian Genome, 21
L. Dow, S. Lowe (2012)
Life in the Fast Lane: Mammalian Disease Models in the Genomics EraCell, 148
M. Winawer, Sandra Gildersleeve, A. Phillips, Daniel Rabinowitz, Abraham Palmer (2011)
Mapping a mouse limbic seizure susceptibility locus on chromosome 10Epilepsia, 52
J. Nadeau, J. Singer, A. Matin, E. Lander (2000)
Analysing complex genetic traits with chromosome substitution strainsNature Genetics, 24
B. Llamas, R. Verdugo, G. Churchill, C. Deschepper (2009)
Chromosome Y variants from different inbred mouse strains are linked to differences in the morphologic and molecular responses of cardiac cells to postpubertal testosteroneBMC Genomics, 10
M. Légaré, F. Bartlett, W. Frankel (2000)
A major effect QTL determined by multiple genes in epileptic EL mice.Genome research, 10 1
A. Ghazalpour, Christoph Rau, Charles Farber, Brian Bennett, L. Orozco, Atila Nas, Calvin Pan, H. Allayee, Simon Beaven, M. Civelek, Richard Davis, Thomas Drake, Rick Friedman, N. Furlotte, S. Hui, J. Jentsch, Emrah Kostem, Hyun Kang, Eun Kang, J. Joo, Vyacheslav Korshunov, Rick Laughlin, Lisa Martin, J. Ohmen, Brian Parks, M. Pellegrini, K. Reue, Desmond Smith, S. Tetradis, Jessica Wang, Yibin Wang, James Weiss, T. Kirchgessner, Peter Gargalovic, E. Eskin, A. Lusis, Renée LeBoeuf (2012)
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traitsMammalian Genome, 23
Gary Churchill, R. Doerge (2008)
Naive Application of Permutation Testing Leads to Inflated Type I Error RatesGenetics, 178
(2012)
Multi-system survey of mouse physiology in C57BL/6J-Chr#PWD/Ph/ForeJ chromosome substitution panel (19 strains). MPD:Svenson2. Mouse Phenome Database web site, The Jackson Laboratory
G. Collin, Y. Asada, D. Varnum, J. Nadeau (2009)
DNA pooling as a quick method for finding candidate linkages in multigenic trait analysis: an example involving susceptibility to germ cell tumorsMammalian Genome, 7
M. Torres, H. Trentzsch, D. Stewart, M. Mooney, J. Fuentes, D. Saad, R. Reeves, A. Maio (2004)
PROTECTION FROM LETHAL ENDOTOXIC SHOCK AFTER TESTOSTERONE DEPLETION IS LINKED TO CHROMOSOME XShock, 24
S. Spiezio, T. Takada, T. Shiroishi, J. Nadeau (2012)
Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of miceBMC Genetics, 13
T. Aitman, Charles Boone, G. Churchill, M. Hengartner, T. Mackay, D. Stemple (2011)
The future of model organisms in human disease researchNature Reviews Genetics, 12
L. Schalkwyk, M. Jung, A. Daser, M. Weiher, J. Walter, H. Himmelbauer, H. Lehrach (1999)
Panel of microsatellite markers for whole-genome scans and radiation hybrid mapping and a mouse family tree.Genome research, 9 9
Takahiro Sakai, Y. Kikkawa, I. Miura, Takeshi Inoue, K. Moriwaki, T. Shiroishi, Y. Satta, N. Takahata, H. Yonekawa (2004)
Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite lociMammalian Genome, 16
H. Grüneberg (1963)
The pathology of development : a study of inherited skeletal disorders in animals
J. Malsen, H. Lith, H. Oppelaar, B. Olivier, M. Kas (2009)
Evidence for Epigenetic Interactions for Loci on Mouse Chromosome 1 Regulating Open Field ActivityBehavior Genetics, 39
H Yonekawa, K Moriwaki, O Gotoh, J Watanabe, JI Hayashi (1980)
Relationship between laboratory mice and the subspecies Mus musculus domesticus based on restriction endonuclease cleavage sitesJpn J Genet, 55
H. Lesscher, M. Kas, S. Elst, H. Lith, L. Vanderschuren (2009)
A grandparent-influenced locus for alcohol preference on mouse chromosome 2Pharmacogenetics and Genomics, 19
K. Ackerman, Hailu Huang, H. Grasemann, C. Puma, J. Singer, Annie Hill, E. Lander, J. Nadeau, G. Churchill, J. Drazen, D. Beier (2005)
Interacting genetic loci cause airway hyperresponsiveness.Physiological genomics, 21 1
B Beutler, EM Moresco (2008)
The forward dissection of afferent innate immunityCurr Top Microbiol Immunol, 321
A. Geraldes, P. Basset, Kimberley Smith, M. Nachman (2011)
Higher differentiation among subspecies of the house mouse (Mus musculus) in genomic regions with low recombinationMolecular Ecology, 20
A. Boyle, K. Gill (2009)
A verification of previously identified QTLs for cocaine-induced activation using a panel of B6.A chromosome substitution strains (CSS) and A/J x C57Bl/6J F2 micePsychopharmacology, 207
S. Yazbek, S. Spiezio, J. Nadeau, David Buchner (2010)
Ancestral paternal genotype controls body weight and food intake for multiple generations.Human molecular genetics, 19 21
森脇 和郎, 城石 俊彦, 米川 博通 (1994)
Genetics in wild mice : its application to biomedical research
Sam Chai, C. Gillombardo, L. Donovan, K. Strohl (2011)
Morphological differences of the carotid body among C57/BL6 (B6), A/J, and CSS B6A1 mouse strainsRespiratory Physiology & Neurobiology, 177
R. Storchová, S. Gregorová, D. Buckiová, V. Kyselová, Petr Divina, J. Forejt (2004)
Genetic analysis of X-linked hybrid sterility in the house mouseMammalian Genome, 15
J. Marshall, J. Mu, Y. Cheah, M. Nesbitt, W. Frankel, B. Paigen (2004)
The AXB and BXA set of recombinant inbred mouse strainsMammalian Genome, 3
S Spiezio, T Takada, T Shiroishi, JH Nadeau (2012)
Impact of genetic divergence on the genetic architecture of complex traits in chromosome substitution strains of miceBMC Genet, 13
H. Fuchs, V. Gailus-Durner, S. Neschen, T. Adler, L. Afonso, J. Aguilar-Pimentel, L. Becker, A. Bohla, J. Calzada-Wack, C. Cohrs, Anna Dewert, Barbara Fridrich, L. Garrett, Lisa Glasl, Alexander Götz, W. Hans, S. Hölter, M. Horsch, Anja Hurt, E. Janas, D. Janik, M. Kahle, Martin Kistler, T. Klein-Rodewald, C. Lengger, Tonia Ludwig, H. Maier, S. Marschall, Kateryna Micklich, G. Möller, B. Naton, C. Prehn, O. Puk, I. Rácz, Michael Räß, B. Rathkolb, J. Rozman, Markus Scheerer, Evelyn Schiller, A. Schrewe, R. Steinkamp, Claudia Stöger, Minxuan Sun, W. Szymczak, Irina Treise, I. Panesso, Alexandra Vernaleken, M. Willershäuser, Annemarie Wolff-Muscate, R. Zeh, J. Adamski, J. Beckers, R. Bekeredjian, D. Busch, O. Eickelberg, J. Favor, J. Graw, H. Höfler, Christoph Höschen, H. Katus, M. Klingenspor, T. Klopstock, F. Neff, M. Ollert, H. Schulz, T. Stöger, Eckhard Wolf, W. Wurst, A. Yildirim, A. Zimmer, M. Angelis (2012)
Innovations in phenotyping of mouse models in the German Mouse ClinicMammalian Genome, 23
H. Yonekawa, K. Moriwaki, O. Gotoh, J. Watanabe, J. Hayashi, N. Miyashita, M. Petras, Y. Tagashira (1980)
RELATIONSHIP BETWEEN LABORATORY MICE AND THE SUBSPECIES MUS MUSCULUS DOMESTICUS BASED ON RESTRICTION ENDONUCLEASE CLEAVAGE PATTERNS OF MITOCHONDRIAL DNAThe Japanese Journal of Genetics, 55
J. Singer, Annie Hill, L. Burrage, Keith Olszens, Junghan Song, M. Justice, William O'Brien, D. Conti, J. Witte, E. Lander, J. Nadeau (2004)
Genetic Dissection of Complex Traits with Chromosome Substitution Strains of MiceScience, 304
A. Matin, G. Collin, Y. Asada, D. Varnum, J. Nadeau (1999)
Susceptibility to testicular germ-cell tumours in a 129.MOLF-Chr 19 chromosome substitution strainNature Genetics, 23
R. Malek, Hong-ying Wang, A. Kwitek, A. Greene, N. Bhagabati, Gretta Borchardt, Lisa Cahill, T. Currier, Bryan Frank, Xianping Fu, M. Hasinoff, E. Howe, N. Letwin, Truong Luu, A. Saeed, Hedieh Sajadi, S. Salzberg, R. Sultana, M. Thiagarajan, J. Tsai, Kathleen Veratti, Joseph White, John Quackenbush, H. Jacob, N. Lee (2006)
Physiogenomic resources for rat models of heart, lung and blood disordersNature Genetics, 38
K. Abe, H. Noguchi, K. Tagawa, Misako Yuzuriha, A. Toyoda, T. Kojima, K. Ezawa, N. Saitou, M. Hattori, Y. Sakaki, K. Moriwaki, T. Shiroishi (2004)
Contribution of Asian mouse subspecies Mus musculus molossinus to genomic constitution of strain C57BL/6J, as defined by BAC-end sequence-SNP analysis.Genome research, 14 12
Annie Hill, E. Lander, J. Nadeau (2006)
Chromosome substitution strains: a new way to study genetically complex traits.Methods in molecular medicine, 128
K. Kotarska, J. Styrna (2012)
Can the partial deletion in the Y chromosome of male mice affect the reproductive efficiency of their daughters?Systems Biology in Reproductive Medicine, 58
Kirsten Youngren, J. Nadeau, A. Matin (2003)
Testicular cancer susceptibility in the 129.MOLF-Chr19 mouse strain: additive effects, gene interactions and epigenetic modifications.Human molecular genetics, 12 4
David Buchner, Jonathan Geisinger, P. Glazebrook, Michael Morgan, S. Spiezio, K. Kaiyala, M. Schwartz, T. Sakurai, A. Furley, D. Kunze, C. Croniger, J. Nadeau (2012)
The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesityMammalian Genome, 23
Irene Whitney, M. Raven, D. Ciobanu, Robert Williams, B. Reese (2009)
Multiple genes on chromosome 7 regulate dopaminergic amacrine cell number in the mouse retina.Investigative ophthalmology & visual science, 50 5
Jessica Walrath, K. Fox, E. Truffer, W. Alvord, Octavio Quiñones, Karlyne Reilly (2009)
Chr 19A/J modifies tumor resistance in a sex- and parent-of-origin-specific mannerMammalian Genome, 20
Jon Beck, Sarah Lloyd, M. Hafezparast, Moyha Lennon-Pierce, J. Eppig, M. Festing, E. Fisher (2000)
Genealogies of mouse inbred strainsNature Genetics, 24
A. Ayadi, M. Birling, Joanna Bottomley, J. Bussell, H. Fuchs, M. Fray, V. Gailus-Durner, Simon Greenaway, Richard Houghton, N. Karp, Sophie Leblanc, C. Lengger, H. Maier, A. Mallon, S. Marschall, David Melvin, Hugh Morgan, G. Pavlovic, E. Ryder, W. Skarnes, M. Selloum, R. Ramírez‐Solís, T. Sorg, L. Teboul, Laurent Vasseur, Alison Walling, Tom Weaver, S. Wells, Jacqui White, A. Bradley, D. Adams, K. Steel, M. Angelis, Steve Brown, Y. Hérault (2012)
Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics ProjectMammalian Genome, 23
Y. Morita, S. Hirokawa, Y. Kikkawa, T. Nomura, H. Yonekawa, T. Shiroishi, Sugata Takahashi, R. Kominami (2007)
Fine mapping of Ahl3 affecting both age-related and noise-induced hearing loss.Biochemical and biophysical research communications, 355 1
Sushant Bhatnagar, A. Oler, M. Rabaglia, D. Stapleton, K. Schueler, Nathan Truchan, Sara Worzella, J. Stoehr, S. Clee, B. Yandell, M. Keller, D. Thurmond, A. Attie (2011)
Positional Cloning of a Type 2 Diabetes Quantitative Trait Locus; Tomosyn-2, a Negative Regulator of Insulin SecretionPLoS Genetics, 7
S. Yazbek, David Buchner, Jonathan Geisinger, L. Burrage, S. Spiezio, G. Zentner, Chang-Wen Hsieh, P. Scacheri, C. Croniger, J. Nadeau (2011)
Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis.Genome research, 21 7
Shiliang Wang, Hua Zhang, Xuming Dai, R. Sealock, J. Faber (2010)
Genetic Architecture Underlying Variation in Extent and Remodeling of the Collateral CirculationCirculation Research, 107
M. Rassoulzadegan, V. Grandjean, P. Gounon, S. Vincent, I. Gillot, F. Cuzin (2006)
RNA-mediated non-mendelian inheritance of an epigenetic change in the mouseNature, 441
L. Burrage, A. Baskin-Hill, D. Sinasac, D. Sinasac, J. Singer, J. Singer, C. Croniger, Andrew Kirby, E. Kulbokas, M. Daly, E. Lander, K. Broman, J. Nadeau (2010)
Genetic resistance to diet-induced obesity in chromosome substitution strains of miceMammalian Genome, 21
K. Paigen (1995)
A miracle enough: the power of miceNature Medicine, 1
K. Moriwaki, N. Miyashita, Akihiko Mita, H. Gotoh, K. Tsuchiya, Hideki Kato, K. Mekada, Chikako Noro, S. Oota, A. Yoshiki, Y. Obata, H. Yonekawa, T. Shiroishi (2009)
Unique inbred strain MSM/Ms established from the Japanese wild mouse.Experimental animals, 58 2
David Buchner, L. Burrage, Annie Hill, S. Yazbek, William O'Brien, C. Croniger, J. Nadeau (2008)
Resistance to diet-induced obesity in mice with a single substituted chromosome.Physiological genomics, 35 1
Hyuna Yang, T. Bell, G. Churchill, F. Villena (2007)
On the subspecific origin of the laboratory mouseNature Genetics, 39
A. Oka, Toshihiro Aoto, Y. Totsuka, R. Takahashi, M. Ueda, Akihiko Mita, Noriko Sakurai-Yamatani, Hiromi Yamamoto, S. Kuriki, N. Takagi, K. Moriwaki, T. Shiroishi (2007)
Disruption of Genetic Interaction Between Two Autosomal Regions and the X Chromosome Causes Reproductive Isolation Between Mouse Strains Derived From Different SubspeciesGenetics, 175
S. Gregorová, Petr Divina, R. Storchová, Z. Trachtulec, Vladana Fotopulosova, K. Svenson, L. Donahue, B. Paigen, J. Forejt (2008)
Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies.Genome research, 18 3
Louis Boell, S. Gregorová, J. Forejt, D. Tautz (2011)
A comparative assessment of mandible shape in a consomic strain panel of the house mouse (Mus musculus) - implications for epistasis and evolvability of quantitative traitsBMC Evolutionary Biology, 11
E. Lander, L. Kruglyak (1995)
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage resultsNature Genetics, 11
S. Keum, D. Marchuk (2009)
A Locus Mapping to Mouse Chromosome 7 Determines Infarct Volume in a Mouse Model of Ischemic StrokeCirculation: Cardiovascular Genetics, 2
M. Laughlin, Kevin Lloyd, G. Cline, D. Wasserman (2012)
NIH Mouse Metabolic Phenotyping Centers: the power of centralized phenotypingMammalian Genome, 23
M. Seiger (1966)
The effects of chromosome substitution on male body weight of Drosophila melanogaster.Genetics, 53 2
K. Paigen, J. Eppig (2000)
A mouse phenome projectMammalian Genome, 11
M. Lam, J. Heaney, Kirsten Youngren, J. Kawasoe, J. Nadeau (2007)
Trans-generational epistasis between Dnd1Ter and other modifier genes controls susceptibility to testicular germ cell tumors.Human molecular genetics, 16 18
Catherine Welsh, Darla Miller, K. Manly, Jeremy Wang, L. McMillan, G. Morahan, R. Mott, F. Iraqi, D. Threadgill, Fernando Villena (2012)
Status and access to the Collaborative Cross populationMammalian Genome, 23
S. Wiltshire, G. Leiva-Torres, S. Vidal (2011)
Quantitative Trait Locus Analysis, Pathway Analysis, and Consomic Mapping Show Genetic Variants of Tnni3k, Fpgt, or H28 Control Susceptibility to Viral MyocarditisThe Journal of Immunology, 186
J. Nadeau, L. Burrage, J. Restivo, Y. Pao, G. Churchill, B. Hoit (2003)
Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations.Genome research, 13 9
A. Oka, Akihiko Mita, Noriko Sakurai-Yamatani, Hiromi Yamamoto, N. Takagi, T. Takano-Shimizu, K. Toshimori, K. Moriwaki, T. Shiroishi (2004)
Hybrid breakdown caused by substitution of the X chromosome between two mouse subspecies.Genetics, 166 2
R. Aksel, J. Kuspira (1968)
Quantitative-genetic analysis of characters in wheat using crosses of chromosome substitution lines (experimental results).Genetics, 58 3
N. Babaya, T. Fujisawa, K. Nojima, M. Itoi‐Babaya, K. Yamaji, K. Yamada, Misato Kobayashi, H. Ueda, Y. Hiromine, S. Noso, Hiroshi Ikegami (2010)
Direct evidence for susceptibility genes for type 2 diabetes on mouse chromosomes 11 and 14Diabetologia, 53
Vicki Nelson, S. Spiezio, J. Nadeau (2010)
Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes.Epigenomics, 2 4
Mayumi Kumazawa, Misato Kobayashi, Fusayo Io, T. Kawai, M. Nishimura, T. Ohno, F. Horio (2007)
Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet Published, JLR Papers in Press, June 26, 2007.Journal of Lipid Research, 48
A. Fortin, Eduardo Diez, D. Rochefort, L. Laroche, Danielle Malo, Danielle Malo, Guy Rouleau, Guy Rouleau, Philippe Gros, Philippe Gros, Emil Skamene, Emil Skamene (2001)
Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.Genomics, 74 1
R. Trammell, T. Liberati, L. Toth (2012)
Host genetic background and the innate inflammatory response of lung to influenza virus.Microbes and infection, 14 1
G. Peltz, A. Zaas, M. Zheng, N. Solis, Mason Zhang, Hong-Hsing Liu, Yajing Hu, Gayle Boxx, Q. Phan, D. Dill, S. Filler (2011)
Next-Generation Computational Genetic Analysis: Multiple Complement Alleles Control Survival after Candida albicans InfectionInfection and Immunity, 79
D. Matthews, E. Chesler, M. Cook, Jody Cockroft, V. Philip, D. Goldowitz (2008)
Genetic Mapping of Vocalization to a Series of Increasing Acute Footshocks Using B6.A Consomic and B6.D2 Congenic Mouse StrainsBehavior Genetics, 38
D. Threadgill, G. Churchill (2012)
Ten Years of the Collaborative CrossG3: Genes|Genomes|Genetics, 2
F. Ratty, E. Lovellette (1967)
Chromosome substitution and radiosensitivity in Drosophila melanogaster.Radiation research, 30 4
M Kumazawa, M Kobayashi, F Io, T Kawai, M Nishimura (2007)
Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat dietJ Lipid Res, 48
A. Oka, T. Shiroishi (2012)
Evolution of the House Mouse: The role of the X chromosome in house mouse speciation
R. Doerge, G. Churchill (1996)
Permutation tests for multiple loci affecting a quantitative character.Genetics, 142 1
M. Nemoto, Y. Morita, Y. Mishima, S. Takahashi, T. Nomura, T. Ushiki, T. Shiroishi, Y. Kikkawa, H. Yonekawa, R. Kominami (2004)
Ahl3, a third locus on mouse chromosome 17 affecting age-related hearing loss.Biochemical and biophysical research communications, 324 4
Laboratory mice are valuable in biomedical research in part because of the extraordinary diversity of genetic resources that are available for studies of complex genetic traits and as models for human biology and disease. Chromosome substitution strains (CSSs) are important in this resource portfolio because of their demonstrated use for gene discovery, genetic and epigenetic studies, functional characterizations, and systems analysis. CSSs are made by replacing a single chromosome in a host strain with the corresponding chromosome from a donor strain. A complete CSS panel involves a total of 22 engineered inbred strains, one for each of the 19 autosomes, one each for the X and Y chromosomes, and one for mitochondria. A genome survey simply involves comparing each phenotype for each of the CSSs with the phenotypes of the host strain. The CSS panels that are available for laboratory mice have been used to dissect a remarkable variety of phenotypes and to characterize an impressive array of disease models. These surveys have revealed considerable phenotypic diversity even among closely related progenitor strains, evidence for strong epistasis and for heritable epigenetic changes. Perhaps most importantly, and presumably because of their unique genetic constitution, CSSs, and congenic strains derived from them, the genetic variants underlying quantitative trait loci (QTLs) are readily identified and functionally characterized. Together these studies show that CSSs are important resource for laboratory mice.
Mammalian Genome – Springer Journals
Published: Sep 8, 2012
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