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Mammalian Genome 12, 256–259 (2001). DOI: 10.1007/s003350010270 Incorporating Mouse Genome © Springer-Verlag New York Inc. 2001 Chromosome heterozygosity and de novo chromosome rearrangements in mammalian interspecies hybrids ,2 1 2 Rachel J. Waugh O’Neill,* Mark D.B. Eldridge, Jennifer A.M. Graves School of Biological Sciences, Division of Environmental and Life Sciences, Macquarie University, NSW 2109 Australia, Austraila Dept. of Genetics, La Trobe University, Bundoora, VIC 3083, Australia Received: 31 July 2000 / Accepted: 15 November 2000 Closely related mammalian species frequently differ in chromo- either an inversion of Xp in the hybrid, or transposition and am- some number and morphology. The source of this variation and the plification of heterochromatic sequences proximal to the NOR, or role it plays in speciation has never been clarified. It is clear from both. Additionally, the normal cross-hybridization of the Meu Y recent research that chromosomal speciation can occur very rap- Chr paint to Xp that is observed in M. eugenii is not present in the idly (Garagna et al. 1997), and one possibility is that it is engen- hybrid (Toder et al. 1997a). dered by hybridization (Reiseberg et al. 1995), possibly by the Meu paints were used to identify the homologous regions in
Mammalian Genome – Springer Journals
Published: Mar 1, 2001
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