Mammalian Genome 9, 320-323 (1998). Mammalian Genome Incorpornnng Mome Gen— © Springer-Verlag New York Inc. 1998 Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice Robert J. Rooney,' Rachael R. Daniels, 3 Nancy A. Jenkins, 4 Debra J. Gilbert, 4 Kristen Rothammer, l Stephan W. Morris, 2,5 Douglas R. Higgs, 2 Neal G. Copeland 4 'Department of Biochemistry, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, Tennessee 38105, USA 'Department of Experimental Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA 3MRC Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK 'Mammalian Genetics Laboratory, ABL-Basic Research Program, NCI -Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA 'Department of Pediatrics, University of Tennessee, College of Medicine, Memphis, Tennessee 38163, USA Received: 30 September 1997 / Accepted: 25 November 1997 Oncogenic transformation by the adenovirus E1A gene is a con- matic cell hybrids showed 100% concordancy for Chr 16, whereas sequence of El A proteins altering the activity or function of cel- all other chromosomes showed discordancies of 8% or higher lular transcription factors that are involved in the regulation of cell
Mammalian Genome – Springer Journals
Published: Mar 20, 2009
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