Chromosomal localization of three human genes encoding members of the TGF-β superfamily of type I serine/threonine kinase receptors

Chromosomal localization of three human genes encoding members of the TGF-β superfamily of type... Brief Data Report 266 Mammalian Genome 9, [2,6]. Two other homologs with about 80% amino acid identity to Chromosomal localization of three human these pancreatic ribonucleases have been found in different bovine genes encoding members of the TGF-(3 tissues: a seminal ribonuclease, which, unlike all other enzymes of the mammalian ribonuclease superfamily, is a homodimer whose superfamily of type I serine/threonine chains are linked by two disulfide bonds [6]; and a brain ribo- kinase receptors nuclease, which, unlike the pancreatic and seminal homologs, has a carboxy-terminal extension with 0-linked oligosaccharide chains E. Roijer, l K. Miyazono, 2 A. -K. Astrom, 1 [6]. The genes encoding these enzymes were cloned from cattle [6, A. Geurts van Kessel, 3 P. ten Dijke, 4 G. Stenman' and unpublished]. These clones were used for cloning the sheep and giraffe genes, which were then sequenced [2]. The seminal 'Laboratory of Cancer Genetics, Department of Pathology, Goteborg ribonuclease appears to be a pseudogene in all ruminant species University, Sahlgrenska University Hospital, SE-413 45 examined so far, except cattle and water buffalo [6,7]. Phyloge- Goteborg, Sweden netic analysis suggests that these three homologs have arisen by Department of Biochemistry, The Cancer Institute, Tokyo, Japanese gene duplication http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Chromosomal localization of three human genes encoding members of the TGF-β superfamily of type I serine/threonine kinase receptors

Loading next page...
 
/lp/springer_journal/chromosomal-localization-of-three-human-genes-encoding-members-of-the-OWv1HzSaoc
Publisher
Springer-Verlag
Copyright
Copyright © 1998 by Springer-Verlag
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900745
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial