Short Communications Incorporating Mouse Genome Mammalian Genome 11, 392–394 (2000). © Springer-Verlag New York Inc. 2000 Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on Chromosome 9 1 2 2 1 Caroline J. Formstone, * Jane Barclay, Michele Rees, Peter F.R. Little Department of Biochemistry, Imperial College of Science, Technology and Medicine, Exhibition Road, London, SW7 2AZ, UK Department of Paediatrics, University College, The Rayne Institute, 5 University Street, London, WC1E 6JJ, UK Received: 19 November 1999 / Accepted: 26 January 2000 Table 1. RT-PCR analysis of the Celsr family within embryonic and adult An exciting new and unique class of developmentally regulated mouse tissue. adhesion-based signaling molecules has been identified recently with the isolation of a number of related cadherin containing Celsr1 Celsr2 Celsr3 seven-pass transmembrane proteins in vertebrates (in the mouse Mouse embryo + + + Celsr1 and flamingo, and in the rat MEGF2 (Hadjantonakis et al. Brain + + + 1997, 1998; Nakayama et al. 1998; Usui et al. 1999) and inverte- Spinal cord + + + brates (Hadjantonakis et al. 1998; Usui et al. 1999). Analysis of the Eye + + + gene isolated
Mammalian Genome – Springer Journals
Published: May 1, 2000
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