Chloroquine/hydroxychloroquine

Chloroquine/hydroxychloroquine Reactions 1704, p96 - 2 Jun 2018 Retinopathy: case report A 32-year-old man developed retinopathy following treatment with chloroquine and hydroxychloroquine [routes, dosages, indications, duration of treatments to reaction onset and outcome not stated]. He had a medical history of systemic lupus erythematosus. He received treatment with hydroxychloroquine and then with chloroquine during 14 years. Subsequently, he exhibited a bilateral loss of visual acuity. Fundus photography demonstrated a characteristic bull’s eye maculopathy, which led to the diagnosis of antimalarial drug retinopathy. Author comment: "Although rare, this side effect may affect 0.008 to 2% of patients under antimalarial drugs and is the cause of permanent untreatable bilateral retinal pigment epithelium damages." "Fundus photography revealed a characteristic "bull’s eye maculopathy" leading to the diagnosis of antimalarial drugretinopathy." Guiot A, et al. Antimalarial drug retinopathy: A typical << Bull’s eyes >> appearance of fundus. Joint Bone Spine 85: 369, No. 3, May 2018. Available from: URL: https://doi.org/10.1016/j.jbspin.2017.05.007 - France 803323687 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Chloroquine/hydroxychloroquine

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46739-7
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p96 - 2 Jun 2018 Retinopathy: case report A 32-year-old man developed retinopathy following treatment with chloroquine and hydroxychloroquine [routes, dosages, indications, duration of treatments to reaction onset and outcome not stated]. He had a medical history of systemic lupus erythematosus. He received treatment with hydroxychloroquine and then with chloroquine during 14 years. Subsequently, he exhibited a bilateral loss of visual acuity. Fundus photography demonstrated a characteristic bull’s eye maculopathy, which led to the diagnosis of antimalarial drug retinopathy. Author comment: "Although rare, this side effect may affect 0.008 to 2% of patients under antimalarial drugs and is the cause of permanent untreatable bilateral retinal pigment epithelium damages." "Fundus photography revealed a characteristic "bull’s eye maculopathy" leading to the diagnosis of antimalarial drugretinopathy." Guiot A, et al. Antimalarial drug retinopathy: A typical << Bull’s eyes >> appearance of fundus. Joint Bone Spine 85: 369, No. 3, May 2018. Available from: URL: https://doi.org/10.1016/j.jbspin.2017.05.007 - France 803323687 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

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