Breast Cancer (2017) 24:714–719 DOI 10.1007/s12282-017-0764-1 ORIGINAL ARTICLE Chemotherapy-induced amenorrhea and the resumption of menstruation in premenopausal women with hormone receptor- positive early breast cancer 1 1 1 1 • • • • Chinami Koga Sayuri Akiyoshi Mayumi Ishida Yoshiaki Nakamura 2 1 Shinji Ohno Eriko Tokunaga Received: 6 September 2016 / Accepted: 16 February 2017 / Published online: 27 February 2017 The Japanese Breast Cancer Society 2017 Abstract resumption of menstruation occurred within 1 year for Background For premenopausal women with breast can- younger patients aged around 30 years, but for those aged cer, information on the effects of chemotherapy and the C35 years, 60% of cases took around 2–3 years for risk of infertility is important. In this study, the effect of resumption. chemotherapy on the ovarian function in premenopausal Conclusions The incidence of CIA, the resumption of women with hormone receptor-positive breast cancer was menstruation and duration of CIA after chemotherapy investigated, with an age-stratiﬁed analysis of the appear- depend greatly on the patient’s age. ance of amenorrhea and the resumption of menstruation after the use of chemotherapy with anthracyclines or Keywords Breast cancer Chemotherapy-induced taxanes. amenorrhea Premenopausal women Hormone receptor Patients and
Breast Cancer – Springer Journals
Published: Feb 27, 2017
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