DOI 10.1007/s10600-018-2400-5 Chemistry of Natural Compounds, Vol. 54, No. 3, May, 2018 1 2 2* Na Liu, Shu-Qi Wang, and Hong-xiang Lou Marchantia species, which are widely used as medicinal plants in China to cure burns, bruises, external wounds, snake bite, etc. , have been studied, and many types of macrocyclic bis(bibenzyls) have been isolated . Macrocyclic bisbibenzyls are produced exclusively in liverworts with a broad range of interesting pharmacological activities, such as antifungal, antimicrobial, anti-inflammatory, antioxidative, anticancer, and skeletal muscle relaxing . Since then, the impressive variety of unusual new chemical entities from this genus continues to fascinate the scientific community for the unusual structures and the powerful biological activities [4–6]. Marchantia paleacea is a common thallus liverwort species known to produce a wide array of distinctive compounds and several bisbibenzyls . As part of our ongoing chemical investigation of Chinese liverworts , we decided to analyze M. paleacea collection from Mount Le of Sichuan Province. We report herein the isolation, identification, and anticancer activities of 10 macrocyclic bis(bibenzyls) together with five triterpenes from this plant. Ten macrocyclic bis(bibenzyls) and five triterpenes were obtained and identified as marchantin C (1) , isomarchantin C (2) , neomarchantin A (3)
Chemistry of Natural Compounds – Springer Journals
Published: Jun 6, 2018
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