Characterization of rabies virus from a human case in Nepal

Characterization of rabies virus from a human case in Nepal Rabies is endemic throughout most of Asia, with the majority of human cases transmitted by domestic dogs ( Canis familiaris ). Here, we report a case of rabies in a 12-year-old girl in the Lalitpur district of Nepal that might have been prevented by better public awareness and timely post-exposure prophylaxis. Molecular characterization of the virus showed 100% identity over a partial nucleoprotein gene sequence to previous isolates from Nepal belonging to the ‘arctic-like’ lineage of rabies virus. Sequence analysis of both partial nucleoprotein and glycoprotein genes showed differences in consensus sequence after passage in vitro but not after passage in vivo . Archives of Virology Springer Journals

Characterization of rabies virus from a human case in Nepal

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Springer Vienna
Copyright © 2011 by Springer-Verlag
Biomedicine; Infectious Diseases; Medical Microbiology ; Virology
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