Characterization of Missense Mutations in the SUP45 Gene of Saccharomyces cerevisiaeEncoding Translation Termination Factor eRF1*

Characterization of Missense Mutations in the SUP45 Gene of Saccharomyces cerevisiaeEncoding... Collection of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1 has been obtained by different approaches. It has been shown that most of isolated mutations cause amino acid substitutions in the N-terminal part of eRF1 and do not decrease the eRF1 amount. Most of mutations studied do not abolish eRF1–eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Characterization of Missense Mutations in the SUP45 Gene of Saccharomyces cerevisiaeEncoding Translation Termination Factor eRF1*

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Publisher
Kluwer Academic Publishers-Plenum Publishers
Copyright
Copyright © 2004 by MAIK “Nauka/Interperiodica”
Subject
Biomedicine; Human Genetics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1023/B:RUGE.0000029148.58151.91
Publisher site
See Article on Publisher Site

Abstract

Collection of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1 has been obtained by different approaches. It has been shown that most of isolated mutations cause amino acid substitutions in the N-terminal part of eRF1 and do not decrease the eRF1 amount. Most of mutations studied do not abolish eRF1–eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Oct 18, 2004

References

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