Characterization of a Paramyxovirus from a Fer de Lance viper( Bothrops jararaca ): partial nucleotide sequence of the putative fusion protein

Characterization of a Paramyxovirus from a Fer de Lance viper( Bothrops jararaca ): partial... During the generation of Expressed Sequence Tags (ESTs) from the Fer de Lance viper ( Bothrops jararaca ) venom glands, a partial cDNA (clone H8) coding for a protein with all the features of a paramyxovirus fusion protein was characterized. It has 920 bp and codes for a partial protein of 279 amino acids. Two potential N-glycosylation sites are present in the sequence which also possesses a typical membrane anchoring domain made of a stretch of hydrophobic amino acids. The polyadenylation signal sequence was identified. When compared to other fusion proteins, it showed the highest sequence similarity (37–39%) with those of human parainfluenza 3 and Sendai virus. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Characterization of a Paramyxovirus from a Fer de Lance viper( Bothrops jararaca ): partial nucleotide sequence of the putative fusion protein

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Publisher
Springer-Verlag
Copyright
Copyright © 2001 by Springer-Verlag/Wien
Subject
Legacy
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s007050170190
Publisher site
See Article on Publisher Site

Abstract

During the generation of Expressed Sequence Tags (ESTs) from the Fer de Lance viper ( Bothrops jararaca ) venom glands, a partial cDNA (clone H8) coding for a protein with all the features of a paramyxovirus fusion protein was characterized. It has 920 bp and codes for a partial protein of 279 amino acids. Two potential N-glycosylation sites are present in the sequence which also possesses a typical membrane anchoring domain made of a stretch of hydrophobic amino acids. The polyadenylation signal sequence was identified. When compared to other fusion proteins, it showed the highest sequence similarity (37–39%) with those of human parainfluenza 3 and Sendai virus.

Journal

Archives of VirologySpringer Journals

Published: Jan 1, 2001

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